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Veterinary medicine / Animal virology / Viruses / Animal diseases / Coronavirus / SARS coronavirus / Severe acute respiratory syndrome / Feline coronavirus / Human Coronavirus NL63 / Biology / Nidovirales / Health


Synthetic recombinant bat SARS-like coronavirus is infectious in cultured cells and in mice Michelle M. Beckera,1, Rachel L. Grahamb,1, Eric F. Donaldsonb, Barry Rockxb, Amy C. Simsb,c, Timothy Sheahanb, Raymond J. Pickl
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Document Date: 2014-02-21 15:04:18

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File Size: 2,43 MB

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City

DBT / New York / Bellinzona / Nashville / /

Company

GenBank / Kopecky-Bromberg SA / AlphaVax Inc. / Ba D V 5 M RB Co / /

Continent

North America / /

Country

United States / China / /

Currency

pence / /

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Facility

National Institute of Allergy / cCarolina Vaccine Institute / University of North Carolina Cystic Fibrosis Tissue Culture Core / Scale bar / Vanderbilt University / University of North Carolina / Chapel Hill / National Institute of Aging / Baric laboratory / /

IndustryTerm

chemical synthesis / reagents/analytic tools / nsp processing / structural modeling algorithms / potential tool / genetic systems / restric tion products / expression vector technology / /

MedicalCondition

delayed brain tumor / productive infection / mixed infection / early human severe acute respiratory syndrome / zoonoses / severe acute respiratory syndrome coronavirus-like virus / severe acute respiratory syndrome / ORF / HAE / clinical disease / hypothetical infectious sequence / infectious chimeric virus / fatal disease / future zoonoses / mouse hepatitis virus / full-length infectious cDNA / murine astrocytoma / infections / influenza / acute respiratory syndrome / murine hepatitis virus / intentional zoonotic-human epidemics / disease / infectious clones / zoonotic severe acute respiratory syndrome / SARS / Ebola / infectious virus / SARS-CoV infection / SARS-CoV infectious clone / murine delayed brain tumor / each infection / persistent infection / infectious virus consisting / SARS-CoV epidemic / infectious diseases / infectious human endogenous retro virus / infection / severe acute respiratory syndrome coronavirus / human disease / Venezuelan Equine Encephalitis / /

NaturalFeature

Chapel Hill / /

Organization

Medicine / and cCarolina Vaccine Institute / University of North Carolina / Immunology / eCystic Fibrosis/Pulmonary Research and Treatment Center / Ingram Cancer Center / National Institute of Aging / National Academy of Sciences / University of North Carolina Cystic Fibrosis Tissue Culture Core / National Institute of Allergy and Infectious Diseases Public Health Service Award P01 AI59943 / Department of Medicine / Mount Sinai School of Medicine / Schematic / Vanderbilt University / Gillings Innovation Fund / University of North Carolina / Chapel Hill / /

Person

Timothy Sheahanb / Amy C. Simsb / Raymond J. Picklesd / Ralph S. Baricb / Lu / Susan Burkett / Rachel L. Grahamb / Barry Rockxb / Sunny Lee / Perry Myrick / Michelle M. Beckera / Mark R. Denisona / Robert E. Johnstonc / Peter Palese / Eric F. Donaldsonb / /

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Position

animal model for SARS / RT / Author / Representative / /

ProvinceOrState

New York / South Dakota / Tennessee / North Carolina / /

Region

southern China / /

Technology

genomics / bioinformatics / electrophoresis / antibodies / structural modeling algorithms / cloning / electroporation / DNA Sequencing / expression vector technology / Molecular evolution / recombination / /

URL

www.pnas.org/cgi/doi/10.1073/pnas.0808116105 / www.pnas.org/cgi/content/full / /

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