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Atypical antipsychotics / Piperidines / Alcohols / Piperazines / Pimavanserin / 5-HT2A receptor / Clozapine / Antipsychotic / Quetiapine / Chemistry / Organic chemistry / Organofluorides


Neurochem Res DOIs11064OVERVIEW On the Discovery and Development of Pimavanserin: A Novel
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Document Date: 2014-12-05 23:10:02

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City

Shanghai / Lonsdorf / Sydney / /

Company

Nordstrom / Thomson / GE / Goldman / ITT / ADP / MPTP / Creative Commons / G. Mills H. Williams ACADIA Pharmaceuticals Inc. / Williams ACADIA Pharmaceuticals Inc. / /

Continent

North America / Europe / /

Country

United States / Australia / Israel / /

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Event

FDA Phase / Product Issues / /

Facility

E pub / /

IndustryTerm

parallel technologies / treatment for Parkinson’s disease / chemical genomics effort / throughput functional assay technology / chemical genomics / treatment of psychosis in Parkinson’s disease / food / Parkinson’s disease therapeutics / treatment of Parkinson’s disease / high-fat food effect / subsequent chemical lead optimization campaign / treatment of agitation in Alzheimer disease / /

MedicalCondition

Springerlink.com Abstract Parkinson’s disease psychosis / DF / dementia / neurodegenerative disease / movement disorder / hallucinations / Parkinsons disease / Nausea / tremor / bradykinesia / visual hallucinations / inverse agonist Background Parkinson’s disease / disease psychosis / agranulocytosis / hypotension / both hallucinations / schizophrenia / disease / head twitch / Parkinson disease / head twitches / vomiting / movement disorders / related disorders / Parkinson’s disease / Keywords Pimavanserin Parkinson’s disease psychosis / Alzheimer disease / neurodegenerative diseases / depression / advanced Parkinson’s disease / /

MusicGroup

Nausea / /

Organization

National Institute of Health / FDA / /

Person

Arch Neurol / Krista McFarland Roger / Roger G. Mills / Ethan S. Burstein / Bradley SR / Hilde Williams / /

Position

investigator / VP / Geyer MA / physician / Neurologist / Bakshi VP / Rusjan PM / Author / reporter / /

Product

haloperidol / SC / M100907 / risperidone / ES / clozapine / ACP-103 / PDP / pimavanserin / motor behavior / /

Technology

Neuroscience / chemical genomics / high-throughput screening / massively parallel technologies / high-throughput functional assay technology / CGI / Pharmacokinetics / drug discovery / /

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