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City London / / Company GlaxoSmithKline / Cox / CASE / Wyeth / Bristol-Myers Squibb / / Facility National Amyloidosis Centre / Renal Function Stable / Baseline laboratory / University College Medical School / Royal Free Hospital / / IndustryTerm Therapy for inflammatory diseases / / MedicalCondition Wells syndrome / inflammatory arthritis / lymphoma / endstage renal failure / Cardiac failure / arthritis / sickle cell anemia / Rheumatoid arthritis / dysfunction / systemic AA amyloidosis / Osteomyelitis / Systemic AA Amyloidosis Helen J. Lachmann / clinically covert inflammatory disease / mesothelioma / periodic fever / solitary cytokine-secreting Castleman’s tumors / epidermolysis bullosa / disorder / progressive perceptive deafness / community-acquired pneumonia / proteinuric renal dysfunction / inexorably progressive disease / renal dysfunction / inflammatory diseases / AA amyloidosis / Familial Mediterranean fever / sepsis / renewed inflammatory disease / murine AA amyloidosis / proteinuria / tumor / end-stage renal failure / necrosis / chronic inflammatory disorders / hereditary / paraplegia / hypertension / arthritides / vasculitis / predominant disease / disease / pressure sores / primary AL amyloidosis / clinically significant liver amyloidosis / chronic / inflammatory disorders / neutropenia / Crohn’s disease / pressure ulcers / toid arthritis / amyloidosis / fever / nephrotic syndrome / inflammatory disorder / urticaria / Juvenile idiopathic arthritis / diseases / autosomal dominant fever syndrome / chronic sepsis / infection / inflammatory disease / Bronchiectasis / amyloid cardiomyopathy / renal failure / inflammation / progressive kidney dysfunction / syndrome / inflammatory / disorders / Tuberculosis / / MedicalTreatment antibiotics / Chemotherapy / Surgery / physiotherapy / immunosuppression / drainage / amputation / Surgical treatments / dialysis / / Organization Centre for Amyloidosis and Acute Phase Proteins / World Health Organization / Department of Medicine / University College Medical School / Department of Primary Care / National Amyloidosis Centre / CONGO RED / Massachusetts Medical Society / / Person Janet A. Gilbertson / ROGER A. RODBY / Julian D. Gillmore / Caroline A. Sabin / Hugh J.B. Goodman / Philip N. Hawkins / J. Ruth Gallimore / / Position investigator / model at yearly intervals / AUTHOR / ARTIST / / Product Leukeran / Cytoxan / cyclophosphamide / / ProvinceOrState M.B. / Massachusetts / / PublishedMedium Natural History / / Region Mediterranean / / Technology antibodies / Chemotherapy / dialysis / / URL www.nejm.org / www.nejm.org / / SocialTag