Medical School-UMDNJ and Cooper Hospital / investigators / study monitor / and independent data monitoring board / N.I.H. / office of Recombinant DNA Activities / Independent Data Monitoring Committee / UMDNJ-Robert Wood Johnson Medical School / Neurosurgical administration / Cooper Hospital / Institutional Review Committee / F.D.A. / Safety Endpoints 1Robert Wood Johnson Medical School / Children’s Hospital of Philadelphia / National Cancer Institute / Monitoring Committee / Coriell Center for Medical Research / Pennsylvania Medical School / Intracranial administration / /
Person
JOAN RUPIN / Gene Vector / PAOLA LEONE / MICHAEL GOLDBERG / ANGELIQUE CAMP / ELIZABETH SASLOW / OLGA GOLDFARB / DAVID SHERA / SCOTT MCPHEE / WILLIAM SHARRAR / EDWIN KOLODNY / JYUU WANG / JOHN HASELGROVE / LARISA LIOUTERMAN / LARISSA BILANIUK / Van Bogaert / JUDE SAMULSKI / Mullen Scales / MARK TESTAIUTI / PETER HURH / P. Leone / Cell / Robert Wood Johnson / /
Position
g.p. / neurosurgeon / referring physician / †Corresponding author / clinical coordinator / investigator / translator / neurologist and a behavioral psychologist / Director / *NINDS Principal Investigator / same neurologist / study biostatistician / reporter / /
Product
protamine sulfate / mannitol / To supplement / T1 / PO2 / to / gene / AAV-2 / /
HUMAN GENE THERAPY 13:1391–1412 (July 20, 2002) © Mary Ann Liebert, Inc. Clinical Protocol Gene Therapy of Canavan Disease: AAV-2 Vector for Neurosurgical Delivery of Aspartoacylase Gene (ASPA)