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City Halifax / / Company Johnston BL Laboratory / / Continent Europe / Asia / North America / / Country Canada / Slovenia / United States / / Facility Dalhousie University / Laboratory Medicine / / IndustryTerm treatment of their Lyme disease / search terms / treatment for Lyme disease / thorough travel history / treatment of Lyme disease / therapy for their Lyme disease / travel history / literature search / treatment of early Lyme disease / / MedicalCondition persistent/recurrent arthritis / B burgdorferi infection / North American and European Lyme disease / late disseminated disease / Bell’s palsy / untreated Lyme disease / acute illness / facial palsy / treated early Lyme disease / Introduction Lyme disease / arthritis / Bannwarth’s syndrome / Borrelia infection / early disseminated disease / Measles / acute Lyme disease / lower inflammatory markers / facial paralysis / human infection / anaphylaxis / pooled infection / post-Lyme disease syndrome / nerve palsy / palsies / usually mild arthralgias / axonal polyradiculoneuropathy / localized erythema migrans / European Borrelia infection / chronic encephalitis / septic arthritis / disease Erythema / endemic / asymptomatic infections / late disease / show refractory arthritis / non-cranial nerve neurologic findings / antibiotic refractory Lyme arthritis / late neurological disease / illness / higher inflammatory markers / Skin Erythema / subacute encephalopathy / carditis / papilledema / strongest predictor septic arthritis / oligoarticular arthritis / early disseminated infection / bilateral disease / persistent subjective musculoskeletal and cognitive symptoms / cognitive impairment / chronic encephalomyelitis / neurologic infection / chronic Lyme disease / fever / erythema migrans lesions / chronic Lyme OR / initial infection / chronic disease / reported infections / Cranial neuropathy / intravenous line infections / early Lyme disease / infection / polyradiculoneuropathy Chronic encephalomyelitis Ocular Retinitis / rash / inflammatory / radiculopathy / erythema migrans / sensory radiculopathy / fetal infections / B. burgdorferi infection / bull’s eye rash / Skin Multiple erythema / palsy / headache / cognitive symptoms / active infection / early localized disease / show arthritis / rash developing / relatively few infections / painful radiculopathy / localized reaction resembling erythema migrans / European Lyme disease / early disease / arthralgias / local Lyme disease / lymphocytoma cutis / fatigue / atrioventricular block / central nervous system infection / lymphadenopathy / residual dysfunction / viral meningitis / acrodermatitis / Lyme disease / infections / refractory arthritis / neurologic symptoms / aseptic meningitis / spastic paraparesis / disease / heart block / especially facial nerve palsy / asymptomatic infection / zoonotic infection / erythema / disseminated disease / pain / persistent infection / synovitis / persistent arthritis / high grade heart block / facial palsies / tachyarrhythmias / inflammation / meningitis / acute infection / myocardial dysfunction / System Manifestation Ocular Conjunctivitis / / MedicalTreatment antibiotic therapy / antibiotics / retreatment / antibiotic prophylaxis / / Organization World Health Organization / Infectious Disease Society of America / Data and Safety Monitoring Board / Nova Scotia Department of Medicine / US Federal Reserve / Capital District Health Authority / Dalhousie University / Public Health Agency / Department of Pathology / Infectious Diseases Society of America / Centers for Disease Control and Prevention / Department of Pathology and Laboratory Medicine / / Person Late Lyme / / Position Short-Form General / Corresponding author / clinical prediction model / / Product ampicillin / erythromycin / Amoxicillin / penicillin / doxycycline / Cefuroxime / azithromycin / cefotaxime / Ceftriaxone / / ProvinceOrState Quebec / Minnesota / New Brunswick / Virginia / Maine / British Columbia / New York / Connecticut / Nova Scotia / Ontario / New Jersey / Vermont / Wisconsin / Maryland / Manitoba / Pennsylvania / Delaware / Massachusetts / New Hampshire / / Region southern Ontario / southeastern Manitoba / eastern Ontario / central Europe / eastern Europe / / URL http / SocialTag 
May 29, 2014 • Volume 40•11 ISSN 1481–8531 Inside this issue: Clinical aspects of Lyme disease As summer approaches, consider this: Lyme disease is expanding its reach in Canada, the United States (US), Europe and