Science Applications International Corporation / ACS / Saldanha S.A. / H. (2002) Systems / PLoS Comp / Elsevier Ltd. / Hammond A.S. / /
Country
United States / Israel / / /
Facility
Sackler Institute of Molecular Medicine / Tel Aviv University / Semmelweis University / National Cancer Institute / NIH National Cancer Institute / /
IndustryTerm
chemical view / active site / free-energy wells / large-scale modeling tools / protein interaction networks / cellular networks / schematic network / functional site / chemical class / cancer therapy / protein networks / interaction network / strain energy spreads / gene transcription networks / machinery / Theoretical network tools / allo-network / free-energy barriers / lower free-energy state / simplified transcriptional network / abnormal processing / target site / schematic energy landscape / energy landscape / treatment of CNS disorders / chemical description / treatment of cancer / catalytic site / perturbation energy / strain energy / allosteric site / cellular network / denser networks / transcription machinery / metabolic networks / transcriptional and signalling networks / gene networks / /
MedicalCondition
human inherited disorders / colorectal cancer / mutant colorectal cancer / hyperparathyroidism / Protein disorder / colon cancer / CNS disorders / Lindau tumor / metastatic breast cancer / neurodegenerative disorders / lung cancers / tumor / network disorder / Cancer / disease / conformational protein disorder / epithelial cancers / prion diseases / tumor necrosis / AIDS / Alzheimer disease / /
MedicalTreatment
chemotherapies / cancer therapy / /
OperatingSystem
Trax / /
Organization
National Cancer Institute / National Institute of Health / National Science Foundation / U.S. Government / Semmelweis University / Department of Human Genetics and Molecular Medicine / Tel Aviv University / Tel Aviv / Center for Cancer Research / School of Medicine / European Commission / Department of Health and Human Services / Department of Medical Chemistry / Sackler Institute of Molecular Medicine / NIH National Cancer Institute / /
Person
Nat / Akt / Hiroaki Kitano / Frederick / / /
Position
driver / Mediator Head / transcriptional Mediator / Mediator / author for internal non-commercial research / D.J. / Corresponding author / RE15 RE31 RE13 RE14 D11 RE12 TF3 D12 RE111 TF1 Head / gigantic Mediator / RE TF Mediator Middle Tail TBP Head / identifying feed-forward / same Mediator / human Mediator / /
Product
efavirenz / valium / Sensipar / Selzentry / /
ProvinceOrState
A.B. / Connecticut / New Mexico / /
PublishedMedium
Elsevier / Cancer Research / PLoS ONE / /
Technology
alpha / genomics / Bioinformatics / gene amplification / metabolic networks / stem cells / DNA binding / apoptosis / drug discovery / thermodynamics / treating cancer / drug design / dom / /
This article appeared in a journal published by Elsevier. The attached copy is furnished to the author for internal non-commercial research and education use, including for instruction at the authors institution and shar