effector binding site / bonded energy term / potential energy function / allosteric site / energy function / energy landscape / energy plot / energy minima / average energy / softsphere energy / distance energy / simulation protocol / free energy profile / protein structure-prediction schemes using energy landscape theory / soft-sphere energy term / contact energy / funneled energy landscape / energy / weighted using the energy / /
Supporting Information Weinkam et al[removed]pnas[removed]SI Materials and Methods Constructing the Allostery Model. For a given protein, the allostery model defines several effector bound and unbound landscapes that