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Leishmania mexicana / Leishmania / Macrophage / Trypanosomatid / Cutaneous leishmaniasis / Amastigote / L. mexicana / Phagocyte / Apoptosis / Biology / Microbiology / Euglenozoa


Leishmania mexicana metacaspase is a negative regulator of amastigote proliferation in mammalian cells
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Document Date: 2012-09-06 06:11:54

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City

Tucson / Paris / Bates / El-Fadili / Nottingham / Paisley / Basel / San Jose / Crawley / Southampton / Mannheim / Cologne / West Sussex / Cambridge / Glasgow / San Diego / /

Company

Pollitt LC / Vector Laboratories / Millipore / Qiagen / Applied Precision Inc. / GE Healthcare / BD Biosciences / Amaxa GmbH / Roper Scientific Inc. / MALT / Zeiss Ltd / LG / Wellcome Trust / Hertz / MCA / VWR International Ltd / Creative Commons / Shimizu / Macmillan Publishers Limited / /

Country

Switzerland / Norway / United Kingdom / Germany / United States / /

Currency

pence / /

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Event

FDA Phase / Product Issues / /

Facility

Institute of Infection / University of Strathclyde / University of Glasgow / Scale bar / College of Medical / University of Wisconsin / University Place / Institute of Pharmacy / /

IndustryTerm

active site / processed products / catalytic site / autocatalytic processing / /

MedicalCondition

trypanosomiasis / macrophage infection / dysfunction / leishmaniasis / ORF / macrophages infection / mitochondrial dysfunction / sustained infection / cells undergoing necrosis / infection / further infection / TB / Leishmania disease / necrosis / Disease / independent infections / MALT lymphoma / Inflammation / heat shock / /

MedicalTreatment

antibiotics / /

NaturalFeature

Shio MT / /

Organization

Wellcome Trust Centre for Molecular Parasitology / V PI / 2Strathclyde Institute of Pharmacy and Biomedical Sciences / College of Medical / Veterinary and Life Sciences / University of Glasgow / Medical Research Council / Institute of Infection / University of Strathclyde / University of Wisconsin / Madison / /

Person

Alexa Fluor / Olivier M. Leishmaniainduced / William Proto / Scott P. Leishmaniasis / Ann V / Ann V-alexa / Mun ˜oz / /

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Position

Loiseau PM / Major / representative / UK *Corresponding author / CPA / /

Product

glycine / Nucleofector / a newly developed system / OL3400 / OL3399 / Nucleofector / Yca1 / mutants / mitochondrial membrane potential / 28 / mutant / S2 / /

ProvinceOrState

Wisconsin / Sussex / Gillingham / /

PublishedMedium

PLoS ONE / /

Technology

X-ray / Apoptosis / gene targeting / antibodies / directed mutagenesis / electroporation / DNA sequencing / /

URL

http /

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