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City Mannheim / Helsinki / Jacksonville / / Company Targos Molecular Pathology GmbH / Cox / Creative Commons / BioMed Central Ltd. / Dako North America Inc. / Eastern Cooperative Oncology Group / / Continent North America / Europe / / Country Germany / United States / / / Event FDA Phase / / Facility Mayo Clinic / / MedicalCondition HER2-positive tumors / HER2-positive primary tumors / centrally confirmed HER2-positive tumors / tumor / earlier disease / tumor HER2 / PRnegative tumors / measurable disease / tumor HER2 mRNA / tumors / disease / Archival tumor / solid tumors / median tumor expression / metastatic breast cancer / HER2-expressing tumor / previously untreated HER2-positive metastatic breast cancer Edith A Perez1 / ER-negative/PR-negative tumors / primary tumor / / MedicalTreatment hormonal therapy / chemotherapy / radiotherapy / adjuvant therapy / / Organization US Food and Drug Administration / / Position investigator / author / HER2 messenger / messenger / / Product T-DM1 / DM1 / TDM4450g / / ProvinceOrState Florida / / Region South America / Central America / / Technology gene amplification / hybridization / chemotherapy / apoptosis / / URL http /
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Perez et al. Breast Cancer Research 2014, 16:R50 http://breast-cancer-research.com/content/16/3/R50 RESEARCH ARTICLE Open Access