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Cell signaling / Pharmacology / Signal transduction / Membrane biology / Receptor antagonist / Adenosine receptor / Receptor / Agonist / Ligand / Biology / Cell biology / G protein coupled receptors


MECHANISMS OF SIGNAL TRANSDUCTION: Identification by Site-directed Mutagenesis of Residues Involved in Ligand Recognition and Activation of the Human A 3 Adenosine Receptor
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IgG / AMP / Robeva A. S. / Rivkees S. A. / Roche Diagnostics / Ligand / Salvatore S. A. / Gilead Sciences / Kim S. A. / basal PLC / Bio-Rad / Stephens / A2A / Amersham Biosciences / /

Country

Germany / Netherlands / United States / Australia / Israel / /

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Facility

Schmiedeberg’s Arch / University of Bonn / Garvan Medical Institute / Israel Institute / Laboratory of Bioorganic Chemistry / University of Pennsylvania / Pharmaceutical Institute / /

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IndustryTerm

aromatic systems / Chemical structures / treatment of ischemic and inflammatory diseases / chemical classes / continuous energy monitoring / putative binding site / /

MusicGroup

MECA / Antagonist / /

Organization

Leiden/ Amsterdam Center for Drug Research / ND ND / Laboratory of Bioorganic Chemistry / Garvan Medical Institute / University of Pennsylvania / Philadelphia / Israel Institute for Biological Research / University of Bonn / Pharmaceutical Institute / /

Person

Dov Barak / Bruce Liang / Neli Melman / Van Rhee / Laurel / Kenneth A. Jacobson / Guo Gao / Christa E. Mu / Gq / Latour / Soo-Kyung Kim / Kyeong Lee / Dunham / Christa E. Müller / Marquez / V / Kelly Soltysiak / /

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Position

Teller / T. D. / Governor / representative / /

ProvinceOrState

Alabama / Maryland / Pennsylvania / /

Technology

Molecular modeling / x-ray / directed Mutagenesis / dielectric / /

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http /

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