View Document Preview and Link Document Date: 2011-09-16 15:10:37 Open Document File Size: 223,70 KB Share Result on Facebook
City ELLENCE / Reference / / Company Adverse Reactions / Pfizer Inc / / Currency CHF / / Event FDA Phase / / Facility Laboratory Test Interactions There / Laboratory Test Interactions USE IN SPECIFIC POPULATIONS / Laboratory Testing / / IndustryTerm glucose solution / treatment of breast cancer / parenteral drug products / chemical incompatibility / cardiovascular systems / rubber stopper / ready-to-use solution / chemical name / diagnostic tool / / MedicalCondition septicemia / septic shock / ventricular tachycardia / local tissue necrosis / local breast cancer / anthracycline-induced cardiomyopathy / primary breast cancer / severe hepatic dysfunction / myelodysplastic syndrome / Hypersensitivity Reactions Alopecia / esophagitis / early breast cancer / non-Hodgkin’s lymphoma / stomatitis / anaphylaxis / premature ventricular contractions / human tumors / acute lymphoid leukemia / conjunctivitis/keratitis / bradycardia / diarrhea / generalized infections / Ocular Conjunctivitis/keratitis / breast cancer / fatal infections / abdominal pain / reversible leukopenia / cardiomyopathy / cancer / inflammatory recall reaction / liver metastasis / chills / Carcinogenesis / neutropenia / characteristic cardiomyopathy / vesication / anal atresia / fever / lethargy / severe leukopenia / Leukopenia/neutropenia / vomiting / breast tumors / severe cellulitis / infection / atrioventricular and bundle-branch block / anuria / depression / spontaneous abortion / rash / Severe local tissue necrosis / symptomatic anemia / severe neutropenia / dormant cardiovascular disease / Severe vomiting / fatal congestive heart failure / Hyperpigmentation / Skin Alopecia Local toxicity Rash / leukopenia / local phlebitis / murine tumors / severe infectious complications / solid tumors / Facial flushing / nausea/vomiting / nausea / Secondary Leukemia / skin rash / thrombocytopenia / alopecia / dose-dependent mucositis / tumor-lysis syndrome / secondary acute myelogenous leukemia / fetal growth retardation / hepatic dysfunction / dose-dependent / reversible leukopenia / leukemias / tachycardia / pulmonary embolism / hypersensitivity / dyspnea / pulmonary edema / organ dysfunction / pruritus / Infections / congestive heart failure / necrosis / thrombophlebitis / refractory secondary leukemia / sinus tachycardia / shock / axillary node tumor / OF TISSUE NECROSIS / erythema / tissue necrosis / mucositis / mainly oral stomatitis / pain / Severe thrombocytopenia / myocardial infarction / lactic acidosis / pleural effusion / heart failure / Urticaria / Advanced solid tumor cancers / tachyarrhythmias / Inflammation / thrombosis / skin and nail hyperpigmentation / acute myelogenous leukemia / anemia / dehydration / / MedicalTreatment platelet transfusions / vaccination / radiotherapy / radiation / contraception / antibiotic therapy / dialysis / radiation therapy / intravenous infusions / combination chemotherapy / antibiotics / chemotherapy / intravenous infusion / chemotherapies / adjuvant therapy / / Organization Administration of ELLENCE / DOSAGE AND ADMINISTRATION / FDA / Infections Administration / / / Position physician / Major / / Product trimethoprim / sodium bicarbonate / allopurinol / Cimetidine / Paclitaxel / ELLENCE / epirubicin hydrochloride / sodium chloride / Cyclophosphamide / Septra / Bactrim / fludarabine phosphate / Fluorouracil / sulfamethoxazole / infusion / / Technology Radiation / chemotherapy / incineration / dialysis / alpha / Pharmacokinetics / / URL www.fda.gov/medwatch / / SocialTag 
HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights do not include all the information needed to use ELLENCE safely and effectively. See full prescribing information for ELLENCE. • The occurrence of secondary acut