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City Mediport / Walker / Indianapolis / Lille / / Company Eli Lilly / Blackwell Publishing Ltd / Aniara Corp / Kohler / Zlokovic BV / / Continent North America / Europe / / Country France / United States / / Currency INR / / / Facility laboratory of Dr Christine Mannhalter / The ChildrenÕs Hospital / University of Colorado Denver / / / IndustryTerm venous access device / therapy of thromboembolic disorders / therapy for some clotting disorders / imaging / venous access devices / / MedicalCondition allergic reaction / thrombophilia / Wideman C. Deficiency / disseminated intravascular coagulation / Haemophilia / Ischemic stroke / dysfunction / severe sepsis / thrombotic and infectious complications / purpura fulminans / thrombocytopenia / thromboembolic disorders / neonatal purpura fulminans / C deficiency / Grafenhofer H. Thrombosis / pulmonary / obesity / disorder / thromboses / congenital blindness / reverses purpura fulminans / MS / lupus / infections / venous insufficiency / massive venous thrombosis / sepsis / orthopaedic injury / inherited thrombophilia / inherent hypercoagulability / C deficiency N. A. GOLDENBERG / priapism / congenital thrombotic disease / necrosis / advanced post-thrombotic syndrome / venous thrombosis / stroke / cognitive impairment / thromboembolism / venous stasis ulcers / skin necrosis / chronic anticoagulant dose / hereditary protein C / post-thrombotic syndrome / Mesenteric venous thrombosis / bilateral vitreal vein thrombosis / protein C deficiencies / ruptured ovarian cyst / deep vein thrombosis / Allergic reactions / venous thromboembolism / osteoporosis / infection / protein C deficiency / deficiency / inflammation / thrombosis / recurrent thrombosis / syndrome / S deficiency / inflammatory / osteoporosis Haemophilia / disorders / / MedicalTreatment invasive procedures / surgery / catheter / major surgery / / Organization United States Centers for Disease Control and Prevention / University of Colorado Denver / National Alliance / Division of Hematology/ Oncology / Department of Pediatrics / Klinisches Institut fu¨r Medizinische / ChildrenÕs Hospital / M. J. MANCO-JOHNSON* *Hemophilia & Thrombosis Center / Department of Medicine / International Committee on Thrombosis and Haemostasis / FDA / / Person Neil A. Goldenberg / Marilyn J. Manco-Johnson / Baxter BioScience / Craig Hooper / Johan Stenflo / Elaine Gray / Christine Mannhalter / / / Position Author / Cumber PM / Anaesthetist / Governor / Major / / Product Xigris / thrive / vitamin K / Xa / / ProvinceOrState Aurora / Prince Edward Island / / PublishedMedium The Authors Journal / / Technology antibodies / Transplantation / pharmacokinetics / magnetic resonance imaging / / URL http / SocialTag 
Haemophilia (2008), 14, 1214–1221 DOI: [removed]j[removed]01838.x ORIGINAL ARTICLE