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Angiology / Guanidines / Dimethylargininase / Asymmetric dimethylarginine / Nitrogen metabolism / Arginine / Endothelium / Exhaled nitric oxide / Nitric oxide / Medicine / Chemistry / Biology


The Endothelial ADMA/NO Pathway in Hypoxia-Related Chronic Respiratory Diseases
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City

dallas / Article / Okayama / /

Company

L. J. Druhan S. P. / K. Gleeson S. A. / New England Journal / Creative Commons / Hindawi Publishing Corporation / /

Country

United States / /

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Event

Product Issues / FDA Phase / /

Facility

Stanford University / American College of Cardiology / University Medical Center Hamburg-Eppendorf / Cardiovascular Institute / /

IndustryTerm

hypertension therapy / Online trapping / gas exchange region / reaction product / chemical redox environment / cellular energy production / treatment of cardiovascular diseases / altered gas-exchange / intercellular regulatory network / /

MedicalCondition

animal cancer / pulmonary artery pressures / Tumour necrosis / chronic lung inflammation / Nature Reviews Cancer / unstable COPD / Arteriosclerosis / Acute and chronic changes / Pulmonary Arterial Hypertension / ischemic stroke / L-Arginine deficiency / dysfunction / chronic thromboembolic pulmonary hypertension / airway inflammation / pulmonary arterial vessels / guanosine monophosphate Chronic / elevated pulmonary arterial resistance / vascular dysfunction / vascular injury / chronic inflammation / injury / non-small-cell lung cancer / Obstructive sleep apnea syndrome PAH / pulmonary vasculature / non-small cell lung cancer / Kirsten rat sarcoma viral oncogene homolog / sustained hypoxia-induced pulmonary vasoconstriction / apneas / angioproliferative disease / Idiopathic pulmonary arterial hypertension IPF / pulmonary development / cardiovascular diseases / porcine small pulmonary vessels / breast cancer / Respiratory Diseases / pulmonary endothelial cells hypoxia / pulmonary vasoconstriction / Asthma / pulmonary vascular remodeling / tumor / pulmonary endothelial cells / chronic hypoxia leads / sleep-disordered breathing / Endotoxic shock / chronic respiratory diseases / cancer / lung inflammation / novel mechanism ameliorating pulmonary hypertension / primary lung cancer / Idiopathic Pulmonary Fibrosis / emphysema / carcinogenesis / endothelial dysfunction / progressive pulmonary vascular remodeling / epithelial cancers / unfavorable pulmonary hemodynamics / Diabetes / pulmonary arterial endothelial cells / pulmonary vascular disease / diseases / inflammatory burden / systemic inflammation / pulmonary arterial pressure / coronary artery disease / ADMA-induced endothelial dysfunction / thickened pulmonary vessels / preeclampsia / Hyperhomocysteinemia / ADMA/NO-Related Endothelial Dysfunction / Pulmonary arterial hypertension PDE / severe asthma / Obstructive Sleep Apnea Syndrome / KRASinduced lung carcinogenesis / fibrosis / sleep apnea patients / result vascular inflammation / vascular disease / small and non-small-cell lung cancer / obstructive pulmonary disease / rat sarcoma / chronic mountain sickness / COPD / peripheral arterial disease / colorectal cancer / obstructive sleep apnea / inflammatory process / endothelial injury / human cancers / alveolar inflammation / intratumoral necrosis / Colitis / decreased DDAH expression potentiate airway inflammation / lung fibrosis / advanced COPD / ischaemic stroke / renal disease / inflammatory cells / porcine distal pulmonary arteries / solid cancers / established experimental COPD / idiopathic pulmonary arterial hypertension / Severe pulmonary hypertension / chronic respiratory lung diseases / chronic hypoxic conditions / local hypoxia-induced pulmonary vasoconstriction resulting / allergic asthma / disease / Atherosclerosis / vascular endothelial dysfunction / hypoxic pulmonary vasoconstriction / lung carcinogenesis / Chronic Obstructive Pulmonary Disease / tumour / Cardiovascular Disease / Bronchial inflammation / chronic lung diseases / pulmonary hypertension / Idiopathic pulmonary fibrosis KRAS / tumor necrosis / chronic hypoxia / Lung Cancer / Sleep apnea / diabetes mellitus / pulmonary circulation / concomitant cardiovascular diseases / chronic diseases / chronic obstructive lung disease / inflammation / thrombosis / respiratory disease / /

MedicalTreatment

nasal continuous positive airway pressure / continuous positive airway pressure / pharmacotherapy / organ transplant / /

Organization

Pulmonary Vascular Disease and Cardiovascular Institute / University Medical Center Hamburg / School of Medicine / the American College / Vera Moulton Wall Center for Pulmonary Vascular Disease / National Academy of Sciences / Department of Medicine-Oncology / Stanford University / Department of Clinical Pharmacology and Toxicology / /

Person

C. R. Morris / S. Ng / V / Silvia M. Arribas / T. E. King Jr. / H. Dayoub / V / S. M. Morris Jr. / A. Pardo / L. Lavrisha / M. Poljakovic / F. A. Kuypers / G. M. Tozer / V / L. Machado / M. Selman / /

Position

mediator / player / major mediator / Academic Editor / /

Product

triad / simvastatin / adenosine / nitro / Sildenafil citrate / vasodilator responses / PDE-5 / /

ProgrammingLanguage

EC / /

PublishedMedium

The American Journal / The Faseb Journal / Proceedings of the National Academy of Sciences / Clinical Science / The American Journal of Respiratory and Critical Care Medicine / The Journal of Clinical Investigation / The New England Journal of Medicine / Molecular Biology / Nature Reviews Cancer / Cancer Research / British Journal of Cancer / /

SportsLeague

Stanford University / /

Technology

apoptosis / CAT / Transplantation / /

URL

http /

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