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Peripheral membrane proteins / Buffers / Sulfonic acids / Lipoxygenase / Arachidonate 5-lipoxygenase / Helicopter landing officer / HEPES / MES / Enzyme / Chemistry / Enzymes / Eicosanoids


Probe Report: Selective Small Molecule Inhibitors of 12-human lipoxygenase (12-hLO)
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Document Date: 2012-11-29 20:05:49

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City

San Diego / Bradford / Waltham / /

Company

COX / ACS / Agilent Technologies / Aldrich Chemical Co. / Sigma Aldrich / Sigma-Aldrich Chemical Company / Bio-Rad / Kalypsys Inc / PerkinElmer / /

Facility

Medical Center Dr. / nL Compound library / University of California / /

IndustryTerm

active site / in-house developed software / pharmaceutical intervention / qHTS assay protocol / potent tool / chemical shift / Chemical shifts / conjugated diene product / substrate solution / chemical / compound solutions / carrier solvent / /

MedicalCondition

inflammatory response / cancers / tumor / prostatevi cancers / cancer / asthmas / prostate cancers / heart disease / diabetes / skin disease / human prostate adenocarcinoma cells / numerous disease / prostate cancer / inflammation / MS / thrombosis / breast cancer / inflammatory diseases / skin diseases / inflammatory response mechanisms / I diabetes / /

MedicalTreatment

AID / /

Organization

University of California / Santa Cruz / NIH Chemical Genomics Center / MH08128301 Screening Center / Medical Center / University of California at Santa Cruz / /

Person

Ajit Jadhav / Elmer Lambda / David J / Christopher P. Austin / Theodore Holman / Elmer Luminescence Spectrometer / P. Austin Assay Submitter / /

Position

rt / Methods General / Fisher / /

Product

Ibuprofen / acetic acid / Dimethyl sulfoxide / /

ProvinceOrState

California / /

Technology

alpha / Chemical Genomics / 12-hLO qHTS assay protocol / /

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http /

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