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Ataxia telangiectasia mutated / P53 / DNA-PKcs / Phosphorylation / DNA repair / Ataxia telangiectasia and Rad3 related / Wee1 / Carcinogenesis / Apoptosis / Biology / Cell biology / Proteins


Phosphorylation of SMC1 by ATR is required for desferrioxamine (DFO)-induced apoptosis
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Document Date: 2011-03-10 05:55:02

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City

Memphis / Cambridge / Gibbstown / San Diego / St. Louis / Santa Cruz / /

Company

Bethyl Laboratories / Millipore / Rockwell / Cell Signaling Technology / Creative Commons / BD Biosciences / Bio-Rad / SMC1 / Macmillan Publishers Limited / /

Country

United States / /

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Event

Product Issues / /

Facility

National Institute of General Medical Sciences Coriell Cell Repositories / S-phase checkpoint / University Place / The MRN complex / Saitama International Medical Center / MRN complex / G2/M checkpoint / The University of Chicago / G2 checkpoint / Jude Children’s Research Hospital / Ouchi laboratory / Johns Hopkins University / University of Minnesota Medical School / /

IndustryTerm

Chemical-induced apoptosis / genotoxic chemicals / chemical reagents / chemicals / /

MedicalCondition

Fanconi anemia / dimer dissociation / Human colorectal carcinoma HCT116 / dysfunction / solid tumors / individual deficiency / hypoxic tumor / breast cancer / Nijmegen breakage syndrome / U2OS human osteosarcoma cell line / tumor / ataxia-telangiectasia / cancer / Disease / ATR deficiency / HCT116 human colon cancer / BRCA1 breast cancer / /

MedicalTreatment

radiation / /

Organization

Saitama International Medical Center / Pritzker School of Medicine / Johns Hopkins University / University of Minnesota Medical School / Department of Medicine / The University of Chicago / Komen Foundation / National Institute of General Medical Sciences Coriell Cell Repositories / Jude Children’s Research Hospital / Avon Foundation / /

Person

Yun Z. Impact / Flores-Riveros J. Transcriptional / /

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Position

Prime Minister / Japan *Corresponding author / representative / Abraham RT / Giaccia AJ / /

Product

hydroxyurea / penicillin / glycine / form / cell / mutant form / cells.15 As / cells / human fibroblasts / HCT116 / fibroblasts / /

ProvinceOrState

South Dakota / California / /

Technology

alpha / radiation / siRNA / antibodies / Biotechnology / ATM / apoptosis / recombination / /

URL

http /

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