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Cell signaling / Tumor necrosis factor-alpha / Apoptosis / Losartan / NF-κB / Fas receptor / Caspase / IKK2 / CCL2 / Biology / Programmed cell death / Cell biology


Life or death by NFκB, Losartan promotes survival in dy2J/dy2J mouse of MDC1A
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Document Date: 2015-03-12 09:33:03


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File Size: 1,80 MB

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Madrid / Petach Tikva / Jerusalem / However / Jena / Indianapolis / San Jose / Santa Cruz / Therefore / IkB-α / Cambridge / Foster City / /

Company

Vector Laboratories / Pediatric Neuromuscular Laboratory / Sigma-Aldrich / Bio-Rad Laboratories / BD Biosciences / TNF / IgG / CBA Software / Carl Zeiss MicroImaging GmbH / Teva Pharmaceutical Industries Ltd. / Creative Commons / Jackson Laboratories / Villalta SA / determined using a BD CBA Software / Macmillan Publishers Limited / /

Country

United Kingdom / Israel / Germany / United States / /

Currency

pence / /

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Event

Product Issues / Judicial Event / /

Facility

Bar Harbor / Savad Institute of Gene Therapy / Scale bar / Hadassah Medical Center / Hebrew University / Hebrew University Medical Center / Schneider Children's Medical Center of Israel / /

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IndustryTerm

enzyme solutions / food / image lab software / μl permeabilisation solution / study protocol / heavy chain / /

MedicalCondition

fiber necrosis / B inflammatory processes / JE / muscular dystrophy type / dysfunction / Laminin alpha2 deficiency / CMD / limb-girdle muscular dystrophy / tumor necrosis factor alpha / chronic inflammation / disorder / inflammatory myopathies / deficient congenital muscular dystrophy / Myopathies / Engvall E. Murine muscular dystrophy / Voit T. The congenital muscular dystrophies / respiratory failure / genetically heterogeneous diseases / Vandenabeele P. Tumor necrosis / muscle disease / different disorders / disuse atrophy / deficiency / antiapoptotic tumor necrosis / inflammatory responses / fibrosis / oculopharyngeal muscular dystrophy / muscular dystrophy / significantly increased serum tumor necrosis / reduced fibrosis / laminin-deficient muscular dystrophy / neuromuscular diseases / muscle weakness / severe hypotonia / MS / necrosis / hypertension / Disease / skeletal muscle atrophy / Muntoni F. Congenital muscular dystrophy / muscle fiber necrosis / limb girdle muscular dystrophy / tumor necrosis / muscular dystrophies / congenital muscular dystrophy / Inflammation / congenital muscular dystrophies / B-cell lymphoma / genetic neuromuscular diseases / /

Organization

Chief Scientist’s Office / 2Goldyne Savad Institute of Gene Therapy / Hebrew University / Hebrew University Medical Center / Ministry of Health / Schneider Children's Medical Center of Israel / Pediatric Neuromuscular Laboratory and Neuropediatric Unit / Neuropediatric Unit / Hadassah Medical Center / /

Person

Ann Neurol / Losartan / Van Erp / Mol Med / Lin A. Blocking / Van Herreweghe / /

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Position

Janssen PM / Israel *Corresponding author / Representative / MyoD messenger / Hunter / /

Product

Losartan / RelA / P-ERK1 / P-p38 / DV / congenital muscular dystrophy / /

ProvinceOrState

South Dakota / /

Technology

Neuroscience / apoptosis / gene expression / genotype / alpha / study protocol / antibodies / Biotechnology / Gene Therapy / laser / /

URL

http /

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