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Apoptosis / Bcl-2 family / Bcl-2 / BH3 interacting-domain death agonist / MCL1 / Fas receptor / Autophagy / Caspase / Bcl-xL / Biology / Cell biology / Programmed cell death


Citation: Cell Death and Disease[removed], e76; doi:[removed]cddis[removed] & 2010 Macmillan Publishers Limited All rights reserved[removed]www.nature.com/cddis GX15-070 (obatoclax) overcomes glucocorticoid
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Document Date: 2010-09-16 06:14:09


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Ann Arbor / Huntsville / Montreal / Mannheim / Frankfurt / Foster City / Richmond / Darmstadt / San Diego / Santa Cruz / /

Company

IgG / hM C LC / Olympus / Millipore / Ford / D Jurkat co / Creative Commons / BD Biosciences / Bio-Rad / PerkinElmer / Macmillan Publishers Limited / /

Country

Germany / Switzerland / United States / Canada / /

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Event

FDA Phase / /

Facility

Virginia Commonwealth University / Massey Cancer Center / VCU Macromolecule Core Facility / BAK complex / College Street / /

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IndustryTerm

apoptotic machinery / cancer therapy / apoptosis machinery / expression-based chemical genomics / chemotherapeutic protocols / /

MedicalCondition

drug-resistant acute lymphoblastic leukemia / DF / JE / multiple myeloma / lymphoma / lymphoid leukemia / chronic lymphocytic leukemia / pediatric acute lymphoblastic leukemia / Human melanoma / MLL-rearranged infant acute lymphoblastic leukemia / childhood ALL / advanced chronic lymphocytic leukemia / advanced hematologic malignancies / Lentivirus infection / dissociation / leukemia / tumor / lymphoblastic leukemia / Cancer / tumors / Disease / hematologic malignancies / acute lymphoblastic leukemia / virus infection / each infection / T-ALL / /

MedicalTreatment

chemotherapy / cancer therapy / /

Organization

National Institute of Health / Department of Internal Medicine / Virginia Commonwealth University / Blanche Hughes Foundation / Massey Cancer Center / CEM GX / /

Person

Barbara Szomju / Kristoffer Valerie / Murthy Madiraju SR / David Gewirtz / /

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Position

hB / Tubulin Tubulin WB / EM /s hB / WB / USA *Corresponding author / representative / /

Product

penicillin / dexamethasone / GX15-070 / Siemens S45 Cellular Phone / prednisone / LY294002 / Bcl-2 / /

ProvinceOrState

Quebec / Virginia / South Dakota / /

RadioStation

Cosialls AM / /

Technology

chemical genomics / AIF / antibodies / Biotechnology / apoptosis / ATG / Cell Signaling Technology / electroporation / Gene Expression / chemotherapy / treating cancer / /

URL

http /

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