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Apoptosis / Proteins / Unfolded protein response / MCL1 / Binding immunoglobulin protein / Autophagy / Bcl-2 / Carcinogenesis / T cell / Biology / Cell biology / Programmed cell death


Anticancer compound Oplopantriol A kills cancer cells through inducing ER stress and BH3 proteins Bim and Noxa
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Document Date: 2014-04-24 08:58:01


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File Size: 2,43 MB

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City

Valencia / Sunnyvale / Indianapolis / Macao / Mountain View / Chicago / MDA / San Jose / St. Louis / Santa Cruz / /

Company

Caliper Life Sciences / Fisher Scientific / Xenogen Corp / Qiagen / Brodsky / HP / Creative Commons / 4State Key Laboratory / System Biosciences / BD Biosciences / Macmillan Publishers Limited / State Key Laboratory / /

Country

United States / /

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Facility

Key Laboratory of Quality Research / State Key Laboratory of Quality Research / University of Chicago / The University of Chicago / University of Macau / Tang Center / Institute of Chinese Medical Sciences / /

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IndustryTerm

cancer prevention / stock solution / protein folding machinery / cancer therapy / Natural products / analysis software / imaging / Animal whole body optical imaging / bioluminescence imaging / fluorescent product / survival systems / performed using the FlowJo analysis software / /

MedicalCondition

OPT-sensitive cancer / Human leukemia KOPN1 / Disease MB231 / multiple myeloma / colorectal cancer / human colorectal cancer / mantle cell lymphoma / human tumor / colorectal cancer cells / OPT significantly inhibited xenograft tumor / kills cancer / xenograft tumor / breast cancer / reduced cancer / tumor / mitochondrial dysfunction / OPT-induced cancer / squamous cell carcinoma / cancer / tumors / MLL-AF9 mouse leukemia / Disease / MDAMB231 cancer / Average tumor / MCL1 significantly sensitized cancer / HCT116 human colorectal cancer / HCT116 cancer / HCT116 colorectal cancer / MDAMB231 human breast cancer / In vivo xenograft tumor / mutant cancer / KOPN1 lymphoblastic leukemia / kill cancer / /

MedicalTreatment

cancer therapy / herbal medicines / /

Organization

The University of Chicago / Chicago / Tang Center for Herbal Medical Research / National Institute of Health / Institute of Chinese Medical Sciences / Institutional Animal Care and Use Committee / University of Chicago / Chicago / Ben May Department for Cancer Research / University of Macau / Tang Center for Herbal Medicine Research / 2Tang Center / /

Person

Walker JR / Laurie Glimcher / Geoffrey Greene / Chong-Zhi Wang / Jianjun Chen / Bim / David Ron / Miq / Ron D. Integrating / Arpad Danos / Ron D. Protein / Ben May / Jinhua Xu / /

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Position

Representative / /

Product

cisplatin / pseudo / Firefly / Paclitaxel / Living Image V2.6.1 software / dimethyl sulfoxide / Living Image V2.6.1 / /

ProvinceOrState

Illinois / Oregon / British Columbia / South Dakota / /

PublishedMedium

Cancer Research / /

Technology

antibodies / Biotechnology / apoptosis / Cell Signaling Technology / treating cancer / spectroscopy / /

URL

http /

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