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SKLB-163, a new benzothiazole-2-thiol derivative, exhibits potent anticancer activity by affecting RhoGDI/JNK-1 signaling pathway
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Document Date: 2014-03-27 11:00:09

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File Size: 2,67 MB

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Guangzhou / Schadendorf / Manchester / Sunnyvale / Oberkochen / Darmstadt / Chongqing / St. Louis / Santa Cruz / /

Company

DakoCytomation Inc / Life Technologies / Western Biotechnology Inc / State Key Laboratory / Merck / Creative Commons / Bio-Rad / Abbott Laboratories / Amersham Biosciences / Macmillan Publishers Limited / /

Country

Germany / Poland / United States / United Kingdom / China / /

Currency

pence / /

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Facility

Sichuan University / State Key Laboratory of Biotherapy / West China Hospital / /

IndustryTerm

cancer prevention / therapy of cancer / stock solution / treatment of cancers / list mode software / ml trypsin solution / formaldehyde solution / cancer treatment / autolysis products / imaging / hypotonic fluorochrome solution / kit manufacturer / therapies for ovarian cancer / Treatment of cancer / /

MedicalCondition

ovarian cancer / significantly inhibited tumor / JE / colorectal cancer / several human tumors / human colorectal cancer / human cancers / Human melanoma / SPC-A1 tumor / Cancer The cancer / melanoma / A375 tumor / non-small cell lung cancer / SPC-A1 human lung adenocarcinoma models / Shacter E. Rho GDP dissociation / diarrhea / MS / human carcinoma / breast cancer / In vivo tumor / cancers / tumor / tumor cells Tumor / cancer / tumors / Disease / hepatocellular carcinoma / cervical cancer / RhoGDI markedly rescued tumor / A375 tumors / human cancer / skin ulcer / malignant melanoma / Olofsson B. Rho guanine dissociation / lung cancer / adenocarcinoma cell line Human / human lung adenocarcinoma cell line SPC-A1 / SKLB-163induced tumor / human cervical cancer / pulmonary adenocarcinoma / widespread and lethal disease / primary tumor / /

MedicalTreatment

rehydration / chemotherapy / radiotherapy / Surgery / molecular therapies / /

Organization

National Cancer Institute / West China Hospital / West China Medical School / Sichuan University / Chengdu / Department of Medical Oncology / Biotherapy and Cancer Center / /

Person

Trypsin Gold (Promega) / Wang W. Potential / /

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Position

China *Corresponding author / Representative / /

Product

cisplatin / penicillin / /

ProvinceOrState

South Dakota / New Foundland and Labrador / Sichuan / /

PublishedMedium

PLoS One / /

RadioStation

Gong FM / /

Region

West China / /

Technology

alpha / genomics / electrophoresis / siRNA / antibodies / Biotechnology / DNA binding / apoptosis / Cell Signaling Technology / chemotherapy / condensation / drug design / gel electrophoresis / drug development / /

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http /

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