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Biguanides / Guanidines / Amides / Orphan drugs / Cancer stem cell / Glioblastoma multiforme / Metformin / Temozolomide / Glioma / Medicine / Chemistry / Brain tumor


New Molecules and Old Drugs as Emerging Approaches to Selectively Target Human Glioblastoma Cancer Stem Cells
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Article / /

Company

S. M. Jeon S. P. / CSC / S. Giri L. C. / AMP / ACS / New England Journal / Creative Commons / H. M. Hassabo N. A. / Hindawi Publishing Corporation / /

Continent

Europe / /

Country

Netherlands / United Kingdom / Jordan / United States / /

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Event

FDA Phase / /

Facility

University of Genova / /

IndustryTerm

viral tools / cancer therapies / Cancer Therapeutics / diabetes prevention / tumor site / Diabetes Care / nonenzymatic chemical degradation process / diabetes treatment / marine natural products / Cancer Prevention / insulin receptor signaling systems / cancer treatment / chemical compounds / treatment of diabetes / tumor energy pathway / social network / intracellular systems / treatment of HER2+ breast cancer / cellular energy homeostasis / /

MedicalCondition

inflammatory response / low-glucose tumor / HER2+ breast cancer / human malignant glioma management / ovarian cancer / Nature Reviews Cancer / glioma stem cells / glioma cells / common primary brain tumor / original tumor / colon and stomach cancer / high-grade glioma / CD133+ colorectal cancer / glioma growth / original tumors / Neuroendocrine tumors / alcohol abuse / early breast cancer / human tumors / large necrosis / human brain tumour / experimental breast cancer / non-small cell lung cancer / IV astrocytoma / breast tumor / Prostate cancer / neurologic deficits / recurrent high-grade glioma / considerably reduced tumor / breast cancer / F Cl Cancer / brain tumor / human acute myeloid leukemia / human glioma tissues / recurrent disease / brain tumors / glioblastoma / II diabetes / glioblastoma cancer / tumor / neck carcinomas / Cancer / human glioblastoma cell growth / tumors / NSCLC / only cancer / rare cancer / chronic treatment / aggressive primary brain tumor / hepatocellular carcinoma / glioblastoma stem cells / hyperglycemia / human cancer / diabetes / metabolic syndrome / several human cancers / BMC Cancer / inflammatory pathways / human hepatocellular carcinoma / CD133+ cancer / acute myeloid leukemia / primary tumor / glioma cell lines / chronic treatments / several tumors / human glioblastoma stem-like cells / human pancreatic cancer / colorectal cancer / metastasis / glioma / solid tumors / directly causing cancer / human cancers / triplenegative breast cancer / sensitive tumors / gliomas / glioblastoma growth / pancreatic adenocarcinoma cells / glioma cell proliferation / endometrial cancer / polycystic ovarian syndrome / differentiated tumor / treated diabetes / glioblastoma derived spheroids / Malignant astrocytic glioma / triple-negative breast cancer / human breast cancer / alcoholism / pancreatic cancer / glioblastoma and clinical strategies / advanced renal-cell carcinoma / several cancer / Reduced cancer / insulin resistance / different tumor / squamous cell carcinoma / disease / glioblastoma multiforme / human lung cancer / human oral squamous cell carcinoma / Molecular Cancer / head carcinomas / cancer stem cells / triple negative breast cancer / preclinical cancer / diabetes mellitus / CD133glioblastoma-derived cancer / operable breast cancer / human pancreatic ductal adenocarcinomas / brain cancer / inflammation / human glioblastoma tumor / cancer stem cell / /

MedicalTreatment

multimodal treatment / radiotherapy / surgery / immunotherapy / radiation / cancer therapies / chemo / adjuvant chemotherapy / Stereotactic radiosurgery / chemotherapy / antibody therapy / adjuvant therapy / /

Organization

World Health Organization / Department of Internal Medicine / FDA / Italian Association for Cancer Research / Centre of Excellence for Biomedical Research / National Academy of Sciences / EMA / MEK / University of Genova / /

Person

R. Rattan / A. Munkarah / P. J. Goodwin / V / R. Ali Fehmi / S. M. Edgerton / Federica Barbieri / M. Della Corte / /

Position

RT / candidate for GBM clinical treatment / human head / Academic Editor / /

Product

cisplatin / Skullcandy G.I. Headphone/Headset / Glucophage / mefloquine / Disulfiram / fluorouracil / adenosine / taxol / NCT01430351 / CXCR4 / TMZ / /

PublishedMedium

ACS Chemical Biology / Drug Discovery Today / Proceedings of the National Academy of Sciences / The New England Journal of Medicine / Nature Reviews Cancer / Cancer Research / PLoS One / Endocrinology / Breast Cancer Research and Treatment / British Medical Journal / British Journal of Cancer / British Journal of Pharmacology / Journal of Clinical Oncology / /

Technology

radiation / high-throughput screening / Stem Cells / apoptosis / Drug Discovery / gene expression / chemotherapy / Neurosurgery / electrophoresis / antibodies / Biotechnology / ATM / cell signaling / /

URL

http /

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