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Cell signaling / Genes / Protein kinases / Membrane biology / Tyrosine kinase / Platelet-derived growth factor receptor / Mitogen-activated protein kinase / Tyrosine-kinase inhibitor / Imatinib / Biology / Cell biology / Signal transduction


BBRC Biochemical and Biophysical Research Communications–1315 www.elsevier.com/locate/ybbrc Breakthroughs and Views
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Document Date: 2006-02-26 12:30:02

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City

Philadelphia / New Orleans / /

Company

Mitsui / S.J. Kirk S.P. / Ligand / C. Akin D.D. / Ó 2005 Elsevier Inc. / ADP / Komatsu / /

Continent

Asia / /

Country

Japan / United States / China / /

Currency

pence / /

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Facility

Kit/STI571 complex / /

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IndustryTerm

active site / phenyl / adenine-binding site / cancer therapy / active-site / actual site / activation loop phosphorylation site / treatment of nasal T-cell lymphoma / treatment of the stable phase of this disorder / side chain / treatment of chronic myelogenous leukemia / human c-kit product / organ systems / reaction product / phosphorylation site / catalytic site / chemical cross-linking experiments / hydroxyl / specific organ systems / therapies for these disorders / /

MedicalCondition

neoplasms / lymphoma Extracellular domain JM segment JM segment JM segment JM / Localized tumors / ovarian germ cell tumors / sinonasal natural killer/T-cell lymphoma / gastrointestinal stromal tumors / mastocytosis Mastocytosis / Seminomas / human cancers / rare ovarian cancers / Mast cell leukemia / leukemia inhibitory factor / small cell lung cancer / germ-cell neoplasms / testicular seminomas / small-cell lung cancer / human gastrointestinal stromal tumors / germ-cell tumors / disorder / mast cell tumors / recurrent disease / seminomas/dysgerminomas / uncommon disorder / tumor / larger tumors / mastocytosis Germ-cell tumor / GIST Seminoma T-cell / cancer / tumors / sinonasal T-cell lymphomas / Dysgerminoma / germ-cell tumor / lymphoma Germ-cell tumor / nervous disorders / ovarian neoplasms / Chronic / diabetes / Nasal T-cell lymphoma / human neoplasms / Dysgerminomas / several human neoplasms / myelogenous leukemia / lung cancer / Targeted cancer / rare disorders / diseases / chronic myelogenous leukemia / metastatic gastrointestinal stromal tumor / nasal T-cell lymphomas / Mastocytosis / acute myelogenous leukemia / metastases / Seminoma / human disease / disorders / human Kita Residues Tumor / /

MedicalTreatment

radiation therapy / combination chemotherapy / chemotherapy / surgery / radiation / cancer therapy / radiation treatment / /

Organization

Louisiana State University Health Sciences Center / Organization of Kit / Department of Biochemistry and Molecular Biology / Department of Biochemistry / /

Person

D. Fabbro / T.K. Sawyer / Kita Residue / K. Hashimoto / R.T. Oliver / Nat / How / Cli / K.N. Lim / V / C.D. Fletcher / D.N. Scheibe / R. Roskoski Jr. / S. Sudarsanam / D. Van den Abbeele / N. Aass / Robert Roskoski Jr. / /

Position

Singer / T. Hunter / G.P. / D.J. / /

Product

carboplatin / cisplatin / Gleevec / glycine / /

ProvinceOrState

Alabama / Louisiana / /

PublishedMedium

Molecular Biology / /

RadioStation

Wait / /

Technology

radiation / bioinformatics / X-ray / Cell signaling / stem cells / human genome / apoptosis / gene expression / chemotherapy / treating cancer / /

URL

www.elsevier.com/locate/ybbrc / /

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