View Document Preview and Link Document Date: 2014-09-25 13:16:04 Open Document File Size: 1,13 MB Share Result on Facebook
City TDP / GFP / Singh / Polymenidou / Cleveland / Bonini / M. / / Company Serpell L. C. / Bethyl Laboratories / Vector Laboratories / Norton / Biologists Ltd / Kowal A. S. / Philips / Bio-Rad / Creative Commons / / Country United States / / / Event FDA Phase / / Facility Johns Hopkins University / University of Pennsylvania / / IndustryTerm functional networks / molecular chaperone machinery / proteostasis network / mammalian disaggregase machinery / / MedicalCondition Lewy body dementia / diverse neurodegenerative disorders / neurodegenerative disease / numerous lethal neurodegenerative disorders / ALS / juvenile amyotrophic lateral sclerosis / amyotrophic lateral sclerosis / sporadic disorder / Huntington disease / familial motor neuron disease / diverse neurodegenerative disease / neurodegenerative disorders / human neurodegenerative disease / disease / amyotrophic lateral sclerosis disease / Parkinson disease / ALS disease / sarcoma / frontotemporal dementia / Parkinson’s disease / Prion-like disorders / familial amyotrophic lateral sclerosis / protein-misfolding disorders / Alzheimer disease / neurodegenerative diseases / familial and sporadic amyotrophic lateral sclerosis / human disease / disorders / / MedicalTreatment dialysis / / Organization National Institute of Health / the University of Pennsylvania / Philadelphia / Perelman School of Medicine / Johns Hopkins University / Packard Center for ALS Research / Department of Biochemistry and Biophysics / / Person Nat / James Shorter / Lee / V / Martin Duennwald / Sanchez / Sue Lindquist / Aaron Gitler / Williamson / Blair / Meredith E. Jackrel / Diaz / / Position Author / King / Singer / Director / Representative data sets / Representative / *Author / / Product polyethylene glycol / Hsp104A503V / glycine / Hsp104V426L / Hsp104 / / ProvinceOrState South Dakota / New Mexico / Pennsylvania / S. K. / / PublishedMedium PLoS ONE / / Technology alpha / protein engineering / Antibodies / Biotechnology / prions / dialysis / / URL http / 
© 2014. Published by The Company of Biologists Ltd | Disease Models & Mechanisms, doi:dmmRESEARCH ARTICLE Potentiated Hsp104 variants suppress toxicity of diverse neurodegenerative di