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Biotechnology / Cell biology / Neurological disorders / Embryonic stem cell / Induced pluripotent stem cell / Spinal muscular atrophy / MECP2 / Neuron / Rett syndrome / Biology / Stem cells / Developmental biology


Saporta et al. Stem Cell Research & Therapy 2011, 2:37 http://stemcellres.com/contentREVIEW Induced pluripotent stem cells in the study of
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South San Francisco / Merville / Philadelphia / Detroit / Geneva / /

Company

Conway AE / Draper / MacDermott AB / Thakor NV / Thomson / Proc Natl Acad Sci U S A / iPierian Inc. / Slaugenhaupt SA / AMP / Goldman SA / GE / BioMed Central Ltd / Shimizu / /

Country

Mali / United States / /

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Event

Product Issues / Product Recall / /

Facility

Arch Gen Psychiatry / /

IndustryTerm

treatment of Rett syndrome / differentiation protocols / carrier state / cell technology / nger nuclease technology / cellular networks / technology makes / specific protocol / important tool / iPS cell technology / chemical / /

MedicalCondition

Rett’s syndrome / neurodegenerative disease / seizures / neurological disorders / Neurological and psychiatric diseases / fundamental disease / familial dysautonomia / dysfunction / ALS / Parkinson disease Parkinson disease / amyotrophic lateral sclerosis / neuropsychiatric disease / Huntington disease / human Huntington’s disease / lateral sclerosis ALS / Nyhan syndrome / common motor neuron disease / genetically complex / late-onset diseases / Rett syndrome Rett syndrome / neurodevelopmental disorders / mitochondrial dysfunction / schizophrenia / Parkinson disease / dysphagia and respiratory failure / Charcot-Marie-Tooth disease / progressive severe mental retardation / novel human disease / common neurodegenerative disorder / Angelman syndrome / movement disorders / Parkinson’s disease / diseases / specific disease / hypotonia / neurological diseases Schizophrenia iPS / common neurogenetic disorder / distinct neurodevelopmental and neurodegenerative diseases / Willi syndrome / disorders / autosomal recessive disease / muscular dystrophy / hereditary sensory and autonomic neuropathies / Day syndrome / each disorder / discrete cellular dysfunction / X-linked autism spectrum disorder / familial dysautonomia using patientspecific iPSCs / X mental retardation / muscular atrophy SMA / peripheral neuropathy / common and diverse cellular disease / acquired / multifactorial disorders / fatal disease / X syndrome / alacrimia / orthostatic hypotension / compensatory tachycardia / Potential disease / neuropsychiatric disorders / lateonset diseases / autosomal recessive disorder / MS / motor neuron disease / amyotrophic lateral sclerosis Angelman syndrome / muscle atrophy / Rett syndrome / spinal muscular atrophy / disease / neurological disease / ALS disease / Lou-Gehrig’s disease / pain / familial amyotrophic lateral sclerosis / neurological diseases / Alzheimer disease / resting tremor / late-onset neurodegenerative disorders / human disease / focused on modeling neurodevelopmental disorders / /

MedicalTreatment

gene therapy / /

Organization

World Health Organization / Department of Neurology / ND ND / Wayne State University School of Medicine / /

Person

Van den Veyver / Irene Griswold-Prenner / Mike Shy / Gene edžƉression / Chamberlain / Berta Strulovici / Ann N Y Acad Sci / /

Position

Cuajungco MP / model for neural development / author / model of motoneuron development and diseases / MP / model of motoneuron development / reporter / /

Product

loxapine / gentamicin / growth factor / tobramycin / valproic acid / recruitment / neuronal differentiation / decrease / /

ProvinceOrState

North Dakota / Michigan / California / /

PublishedMedium

Lippincott Williams & Wilkins / /

Technology

neuroscience / high-throughput screening / differentiation protocols / stem cells / specific protocol / drug screening / drug discovery / gene expression / applying iPS cell technology / gene targeting / genotype / cell technology / transplantation / gene therapy / iPS cell technology / nger nuclease technology / drug development / regenerative medicine / /

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