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City Deoxyribozyme / Kano / Kitamura / Baltimore / Transactivator / Cambridge / Silverman / K. / Elowitz / Wiley / Synthesizing Biomolecule / / Company Intercellular Networks / ACS / Nucleic Acid Enzyme-Based Computation Systems / Mironov A. S. / XXX ACS Synthetic Biology Review / Nucleic Acid Enzyme-Free Computation Systems / / Country United States / / / Event Movie Release / / Facility National Institute of Health / Johns Hopkins University / / / IndustryTerm intracellular networks / long processing time / transcription-based logic device / information processing / logic devices / network-based logic device / endogenous cellular machinery / representative ribozyme-based logic device / apoptosis-controlling device / plug-and-play systems / transcription-free logic device / biomolecular devices / tetracycline chemical dimerizers / non-genetic circuit devices / to computational devices / proteomics technology / in vitro logic devices / integrated riboswitch devices / gene devices / machinery / faster processing power / plug-and-play devices / representative miRNA-based logic device / nucleotide-based computational systems / biological applications / signal processing / coveted technology / cellular information processing / output devices / cell-based and cell-free biomolecule-based logic devices / translation machinery / food / aptamer-based logic device / protein-based logic systems / information processing abilities / representative transactivator-based logic device / plasmid-based logic device / enzyme-based computational systems / mRNA systems / decision-making networks / mRNA-based logic device / intron site / artificial device / representative riboswitch-based logic device / genetic networks / protein-based biomolecular devices / cell-based and cell-free systems / potential clinical applications / enzyme-based logic device / migration-based logic device / in vitro biomolecule-based logic devices / biological tools / computer software / representative nanorobot-based logic device / nutrient status-dependent logic device / above-mentioned bimoleculer-based computational systems / pair-based logic device / synthetic devices / miRNA-based plug-and-play device / computing / logic device / elementary computing / miRNA-based synthetic cell death device / regulatory device / molecular processors / communication networks / combinatorial repetitive chemical selection process / orthogonal biomolecular devices / chemicals / representative network / operational machinery / deoxyribozyme-based logic device / representative amber suppressor tRNA-based logic device / / MedicalCondition herpes / cancer / specific cancer / / MedicalTreatment drug delivery system / / Movie A. D. / / Organization National Institute of Health / Department of Biomedical Engineering / Department of Cell Biology / Center for Cell Dynamics / Japan Science and Technology Agency / Johns Hopkins University / School of Medicine / / Person Amber Suppressor / Nat / Breaker et al. identi / Vogel / V / Robert DeRose / Shiva Razavi / Matthias Jakob Schleiden / Rudolf Virchow / Theodor Schwann / / / Position model for metabolic pathway based computing / synthetic biologist / representative network plasmid-based logic device / PRESTO investigator / AUTHOR INFORMATION Corresponding Author *Phone / Representative / reporter / / Product erythromycin / theophylline / ganciclovir / adenosine / / ProvinceOrState Maryland / New York / S. K. / M. B. / / Technology proteomics technology / siRNA / molecular processors / hybridization / integrated circuits / human genome / apoptosis / coveted technology / biofuels / DNA Chip / gene expression / drug delivery system / bioelectronics / / SocialTag 
Review pubs.acs.org/synthbio Synthesizing Biomolecule-Based Boolean Logic Gates Takafumi Miyamoto,† Shiva Razavi,†,‡ Robert DeRose,† and Takanari Inoue*,†,§ †