| Document Date: 2007-08-15 06:46:13
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City Hamburg / / Company Jackson Laboratory / / Country Germany / Guinea / United States / / Currency pence / / / Event Product Issues / / Facility Scale bar / Ostm1 complex / N terminus / / IndustryTerm approximate cleavage site / online version / antibody binding site / consensus site / predicted signal peptide cleavage site / / MedicalCondition Albers-Scho¨nberg disease / disease / mild osteopetrosis / Severe osteopetrosis / human autosomal recessive osteopetrosis / severe malignant autosomal recessive osteopetrosis / intermediate osteopetrosis / autosomal dominant osteopetrosis / Retinal degeneration / osteopetrosis / lysosomal storage disease / bone resorption / human genetic disease / Severe malignant osteopetrosis / human malignant infantile osteopetrosis / infantile malignant osteopetrosis / / Position Author Information Reprints / J. Bone Miner / RT / / Product mice4 / / Technology antibodies / cloning / / URL www.nature.com/nature / /
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Vol 440|9 March 2006|doi:[removed]nature04535 LETTERS ClC-7 requires Ostm1 as a b-subunit to support bone resorption and lysosomal function Philipp F. Lange1, Lena Wartosch1, Thomas J. Jentsch1 & Jens C. Fuhrmann1