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Transcription factors / Biotechnology / Cell biology / Carcinogenesis / Hypoxia-inducible factors / Glioblastoma multiforme / Temozolomide / CD133 / Glioma / Biology / Medicine / Brain tumor


BMP2 sensitizes glioblastoma stem-like cells to Temozolomide by affecting HIF-1α stability and MGMT expression
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Document Date: 2012-10-18 05:59:16

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Glostrup / Bergisch Gladbach / Padova / Beverly / Brea / Milano / Vancouver / Cleveland / Milan / Basel / St. Louis / Santa Cruz / Hilden / Minneapolis / Helsinki / Madison / Rome / Cambridge / Lausanne / Melville / London / Chicago / /

Company

Hjelmeland AB / HIF / Euroclone S.p.A. / Roche Diagnostics / Millipore / Sigma-Aldrich / Amersham / Cell Signalling Technologies / Qiagen / GE Healthcare / BD Biosciences / Covance / IgG / Nikon / Beckman Coulter / Becton Dickinson / Oncohematology Laboratory / Macmillan Publishers Limited / /

Country

Switzerland / Canada / United Kingdom / Denmark / Germany / Italy / United States / /

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Event

Product Issues / FDA Phase / /

Facility

Bar graph / Integrative Biosciences Institute / Lerner Research Institute / University of Padova / Padova University Hospital / /

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IndustryTerm

cancer therapy / gas-controlled expansion / radiological imaging / restriction site / /

MedicalCondition

GBM cancer stem cell / common brain tumour / glioma stem cells / G Basso1 Glioblastoma / glioma cells / glioblastoma cells / high-grade glioma / dysfunction / brain tumours / human brain tumour / xenograft tumours / Brain tumour / brain tumor / Glioblastoma / Epigenetic-mediated dysfunction / cancer / glioblastoma stem cells / highly proliferative brain tumour / glioblastomas / stem-like glioblastoma cells / glioblastoma derived cells / tumours / Cancer Glioblastoma multiforme / glioma / Altaner C. Glioblastoma / SCID mice / core-derived tumours / J Cancer / additional tumours / human glioma cell growth / glioblastoma stem-like cells / GBM tumours / glioblastoma and clinical strategies / dissociation / Disease / glioblastoma multiforme / different tumours / tumour / cancer stem cells / common and lethal primary brain tumour / SCID / malignant gliomas / Mol Cancer / /

MedicalTreatment

radiotherapy / surgery / radiation / cancer therapy / image guided surgery / Neurosurgery / chemotherapy / /

NaturalFeature

Charles River / /

Organization

Integrative Biosciences Institute / Department of Molecular Cardiology / Italian Association for the Fight against Neuroblastoma / Italian Association for Cancer Research-AIRC / Department of Neuroscience / Ecole Polytechnique Fe´de´rale de Lausanne / Department of Biomedical Sciences / Padova University Hospital / University of Padova / Ethical Committee / Lerner Research Institute / /

Person

Aria III / Della Puppa / O.V. Razorenova / Sanchez-Martin M. Brain / /

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Position

Professor / HRE-luciferase reporter / representative / Italy *Corresponding author / Hyperfilm MP / Cao / reporter / HRE-reporter / /

Product

BMP-2 / form / pcDNA3 / following BMP2/TMZ treatment / transcription / generation / CD133 / /

ProgrammingLanguage

L / /

ProvinceOrState

California / Massachusetts / /

PublishedMedium

Cancer Research / PLoS One / /

Technology

Neuroscience / radiation / BMP / siRNA / stem cells / apoptosis / gene expression / chemotherapy / treating cancer / Neurosurgery / antibodies / Biotechnology / ATG / http / regenerative medicine / containing HIF-1a siRNA / /

URL

http /

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