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Anatomy / Monomethyl auristatin E / Monoclonal antibody therapy / Monoclonal antibodies / Antibody-drug conjugate / Anaplastic large-cell lymphoma / CD30 / Targeted therapy / Ibritumomab tiuxetan / Medicine / Biology / Immunology


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City

Topsham / Washington DC / Bothell / Indianapolis / Milwaukee / Meriden / San Jose / Camarillo / Wilmington / Milford / /

Company

McMillan SA / Hawkins SA. / Agilent / Zellkulturen GmbH / Donaldson / CellQuest Software / IgG / Fairchild / cAC10-vcMMAE / Becton Dickinson / Seattle Genetics / /

Country

Germany / /

/

Event

FDA Phase / /

Facility

University of Texas Southwestern Medical Center / /

IndustryTerm

atmospheric pressure chemical ionization source / cancer therapy / potential product / tumor site / treatment of cancer / drug-linker degradation products / drug-linker solution / drug-linker stock solution / stock solution / clinical applications / treatment of acute myeloid leukemia / marine natural product / model systems / treatment of Hodgkin’s disease / sheath gas flow rate / ice-cold staining media / cold-reduced antibody solution / /

MedicalCondition

rheumatoid synovitis / HDLM2 Hodgkin disease / JE / lymphoma cell lines / rituximab-refractory tumors / large granular lymphoma cell line / multiple sclerosis / anaplastic large cell lymphoma cell line Karpas / complete tumor / head tumors / severe disease / large colon tumor / Hodgkin disease / only slight tumor / Leukemia / tumor / cancer / tumors / CD30-expressing hematologic malignancies / L540cy tumors / anaplastic large cell lymphoma / non-Hodgkin lymphoma / inflammatory disease / L540cy HD tumor / lymphoma lines / acute myeloid leukemia / inflammatory / specific cancers / HD tumors / lymphoma / Hodgkin’s disease / ALCL tumor / well-established tumors / complete / durable tumor / subcutaneous and disseminated tumor / MS / localized scleroderma / neck tumors / chronic autoimmune / breast cancers / different tumor / immunologic diseases / severe combined immunodeficiency / disease / average tumor / L540cy Hodgkin disease cells / subcutaneous disease / Hematology Introduction The tumor necrosis factor / large granular lymphoma cell line YT / nM L540 Hodgkin disease / partial tumor / lymphomatoid papulosis / disseminated disease / epithelial tumors / human anaplastic large-cell lymphoma xenografts / antigen-positive tumor / SCID / hindlimb paralysis / analyzed using LCMS/MS / /

MedicalTreatment

Immunotherapy / cancer therapy / chemotherapy / radioimmunotherapy / antibody therapy / /

OperatingSystem

XP / /

Organization

University of Texas Southwestern Medical Center / Dallas / Society of Hematology / American Society of Hematology BLOOD / American Society / Animal Care and Use Committee / /

Person

Ron DeBlanc / Barth S. Recombinant / Raji Burkitt / Damon L. Meyer / Che-Leung Law / Alan F. Wahl / Bruce J. Mixan / Nick-Vincent Maloney / Younes A. Rituximab / Dana F. Chace / Kristine A. Gordon / Starr X. Rejniak / Brian E. Toki / Harlan Bioproducts / Svetlana O. Doronina / Peter D. Senter / Clay B. Siegall / Joseph A. Francisco / Phil Thorpe / Charles G. Cerveny / Kerry Klussman / Alan F. Wahl Updated / /

Position

King / representative / /

Product

mitomycin / Mylotarg / paclitaxel / DTPA / After injection / ES / dimethyl sulfoxide / Taxol / CD30 / CD33 / /

ProgrammingLanguage

DC / /

ProvinceOrState

Washington / YT / /

Technology

Apoptosis / drug delivery / chemotherapy / treating cancer / ADC technologies / ADC / antibodies / polymerization / DNA synthesis / targeted chemotherapy / by inhibiting the polymerization / /

URL

http /

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