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T cells / Dendritic cell / T helper cell / CpG Oligodeoxynucleotide / CXCR3 / CCL2 / TLR9 / Antigen-presenting cell / CD40 / Biology / Immune system / Anatomy


FC-98 Regulates TLR9-Mediated of CXCL-10 Expression in Dendritic Cells via MAPK and STAT1 Signaling Pathway
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City

Shanghai / Minneapolis / Madison / La Jolla / Article / San Diego / St. Louis / /

Company

Gibco Inc. / Quest software / A. Dunne N. A. / Alpha Innotech Corporation / Sigma-Aldrich / GraphPad Software Inc. / PeproTech Inc. / FluorChem FC2 System / Creative Commons / BD Biosciences / DojinDo Laboratories / Hindawi Publishing Corporation / analyzed using Cell Quest software / /

Country

Germany / Japan / United States / China / /

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Event

FDA Phase / /

Facility

Jiangsu Key Laboratory of Molecular Medicine / Scripps Institute / Animal Research Center of Yangzhou University / Nanjing University / The State Key Laboratory of Pharmaceutical Biotechnology / National Cancer Institute / Institute of Functional Biomolecules / /

IndustryTerm

stock solution / treatment of numerous diseases / treatment of CXCL-10associated diseases / stop solution / treatment of CXCL-10 mediated diseases / innate and adaptive immune systems / substrate solution / chemical structure / /

MedicalCondition

mice’s sepsis / viral infection / Mycobacterium tuberculosis infection / autoimmune liver diseases / autoimmune inflammation / inflammatory diseases / autoimmune diseases / autoimmune disorders / necrosis / cancer / disease / malaria / tumour / malaria infection / immune diseases / viral infections / diseases / Leishmania donovani infection / CXCL-10associated diseases / coxsackievirus myocarditis / infectious diseases / human glioma cells / infection / inflammation / numerous diseases / Rabies virus / /

MedicalTreatment

Molecular Therapy / vaccination / Immunotherapy / gene therapy / /

Organization

National Cancer Institute / Yangzhou University / Scripps Institute / Division of Immunology / School of Life Sciences / Graduate School / National Natural Science Foundation of China / Nanjing University / Nanjing / Institute of Functional Biomolecules / Scientific Research Foundation / Animal Research Center / /

Person

Huan Dou / Thomas Griffith / S. J. van Vliet / Wei Gong / /

Position

Dual-Luciferase Reporter / Academic Editor / Luciferase Reporter / representative / forward / reporter / Marshall / /

Product

penicillin / Quest / dimethyl sulfoxide / FC-98 / /

ProvinceOrState

California / /

PublishedMedium

Journal of Virology / Current Opinion / Nature Reviews Immunology / Journal of Experimental Medicine / PLoS ONE / Journal of Immunology / The Journal of Clinical Investigation / Current Opinion in Immunology / /

Technology

Antibodies / Biotechnology / Apoptosis / gene therapy / Cell Signaling Technology / Drug Delivery / Gene Expression / /

URL

http /

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