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Carcinogenesis / Cellular processes / Cell lines / Alkylating antineoplastic agents / Ammine complexes / Cisplatin / Cancer stem cell / Lung cancer / Non-small-cell lung carcinoma / Medicine / Biology / Chemistry


Resistance to DNA-damaging treatment in non-small cell lung cancer tumor-initiating cells involves reduced DNA-PK/ATM activation and diminished cell cycle arrest
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Document Date: 2013-01-31 09:57:49


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File Size: 1,81 MB

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City

Bergisch Gladbach / Stockholm / Basel / Santa Cruz / Sollentuna / Cambridge / Fremont / London / Ta¨by / Solna / Go¨ttingen / /

Company

Hjelmeland AB / Vector Labs Inc. / D2 / Roche Diagnostics / Thermo Fisher Scientific / Millipore / Sigma-Aldrich / treatmentnaive LC / Odyssey Sa / Qiagen / Cheng LC / GE Healthcare / Pharmacia / CellQuest Software / Bethyl Laboratories / IgG / Karolinska Institutet Research Funds / Creative Commons / Macmillan Publishers Limited / /

Country

Switzerland / United Kingdom / Germany / Sweden / United States / /

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Event

Product Issues / /

Facility

Karolinska University Hospital / Uppsala University / checkpoint Characterization / /

IndustryTerm

active site / solute carrier family / lung cancer treatment / amplified product / damage response machinery / stem cell media / cell dissociation solution / cancer treatment / complementation / cellular signaling networks / damage signaling network / /

MedicalCondition

Laterra J. Cancer / lymphocytic leukemia / JE / large-cell and squamous carcinoma / mouse tumor / non-small-cell lung cancer / non-small cell lung cancer / lung adenocarcinoma / breast cancer / non-small cell lung cancer tumor / aggressive glioblastoma subtype / glioblastoma / adenocarcinoma / median tumor / tumor / large cell carcinomas / cancer / tumors / NSCLC / Varticovski L. Lung cancer / cisplatin-resistant human ovarian cancer / mock-treated bulk tumors / large cell/adenocarcinoma / human hepatocellular carcinoma / tumorigenic lung cancer / gastric cancer / Fanconi anemia / dimer dissociation / platinum-containing cancer / also called cancer / metastasis / glioma / stem-like cancer / self-renewing lung cancer / gliomas / cell dissociation solution / bulk tumors / MS / glioma and medulloblastoma tumor / ataxia / different tumor / squamous cell carcinoma / adenocarcinomas / Highly tumorigenic lung cancer CD133 / LC disease / Disease / Cancer Lung cancers / Mycobacterium tuberculosis / human lung cancer / large cell carcinoma / Female SCID / J Gynecol Cancer / assessed tumor / lung cancer / liver cancer / Disease TICs / SCID / /

MedicalTreatment

radiotherapy / radiation / chemo / chemotherapy / /

MusicAlbum

TICs / /

Organization

Department of Oncology-Pathology / Karolinska Biomics Center / Swedish National Board of Health and Welfare / Stockholm Cancer Society / European Union / Swedish Cancer Society / Stockholm County Council / Karolinska Institutet and Karolinska University Hospital / Swedish Research Council / Karolinska University Hospital / Roswell Park Memorial Institute / Animal Ethical committee in Stockholm / Uppsala University / /

Person

Lyle S. Quiescent / /

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Position

RT / representative / CT/RT / increased CT/RT / Tin VP / conventional CT/RT / driver / Increased RT / Sailor / Alfaro MP / Sweden *Corresponding author / Marshall / /

Product

cisplatin / Sigma / Puma / TICs / Polaroid a300 Digital Camera / activation / CT response / phosphorylation / cell cycle arrest / G2/M / checkpoint Characterization / /

ProvinceOrState

Connecticut / South Dakota / /

PublishedMedium

PLoS One / /

Technology

radiation / siRNA / stem cells / apoptosis / gene expression / chemotherapy / recombination / electrophoresis / antibodies / Biotechnology / ATM / Cell Signaling / /

URL

http /

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