Research Center / ER store / Institute of Biological Chemistry / National Taiwan University / terminal His-tagged CCT-b / California Institute of Technology / CCT complex / /
IndustryTerm
cancer therapy / protein networks / cell culture media / machinery / cancer treatment / eluted protein solution / fresh media / pharmaceutical inhibition / protein degradation systems / pharmaceutical inhibitor / protein trafficking/degradation systems / external media / chemicals / /
MedicalCondition
novel anti-MDR cancer / uterine cancer / tanespimycin-resistant cancer / lentivirus-driven shRNA infection / taxane-resistant tumors / tumor / Cancer / Disease / MDR cancer / cultured cancer / clinical tumors / tumor necrosis / infection / both cancer / multidrug-resistant cancer / /
MedicalTreatment
chemotherapy / cancer therapy / /
MusicGroup
B / A and C / A / / C / B. VCP / A. / /
Organization
National Taiwan University / Taipei / California Institute of Technology / Bioresource Collection and Research Center in Taiwan / Institute of Biological Chemistry / TG administration / /
Targeting β-tubulin:CCT-β complexes incurs Hsp90- and VCP-related protein degradation and induces ER stress-associated apoptosis by triggering capacitative Ca2+ entry, mitochondrial perturbatio