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Apoptosis / Proteins / Immune system / Cell signaling / Caspase 3 / Caspase / Fas receptor / XIAP / Poly ADP ribose polymerase / Biology / Cell biology / Programmed cell death


The HECTD3 E3 ubiquitin ligase facilitates cancer cell survival by promoting K63-linked polyubiquitination of caspase-8
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Document Date: 2013-11-28 09:52:31


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File Size: 3,15 MB

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City

Rockville / Austin / Eppendorf / Kunming / Cullin3 / St. Louis / Santa Cruz / /

Company

IgG / E3 / E6-AP 1 Key Laboratory / Genentech / TNT Quick Coupled Transcription/Translation Systems / US Biomax Inc / Fas Ab / ProSci Inc. / Tepnel Company / anti-HECTD3 Ab / anti-CD95 Ab / 2State Key Laboratory / Macmillan Publishers Limited / /

Country

France / United States / China / /

Currency

pence / /

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Event

FDA Phase / /

Facility

Flag-tagged TRAIL / Kunming Institute of Zoology / Peking Union Medical College / E6-AP COOH terminus / Key Laboratory of Molecular Oncology / stable HECTD3 / Medical College of Wisconsin / 3Wadsworth Center / University of Texas Southwestern Medical Center / State University of New York / terminal DOC / Cancer Institute / Albany Medical College / University of Texas / Key Laboratory of Animal Models / University of Michigan / COOH terminus / ng/ml TRAIL / /

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IndustryTerm

cancer treatment / ubiquitination site / /

MedicalCondition

tissues carcinomas / human cancers / HeLa cervical cancer cell line / invasive carcinomas / breast carcinomas / breast and breast carcinoma / several breast cancer / prostate cancer / breast cancer / tumor / breast cancers / cancer / tumors / Disease / breast cancer cell line / breast tumors / Mol Cancer / /

MusicGroup

anti-FLAG / Cell / /

Organization

Medical College of Wisconsin / Milwaukee / New York State Department / Key Laboratory of Animal Models and Human Disease Mechanisms / 3Wadsworth Center / University of Michigan / Chinese Academy of Sciences & Yunnan / 4The Center for Cell Biology and Cancer Research / State University of New York / Albany Medical College / School of Public Health / Medical Sciences and Peking Union Medical College / University of Texas Southwestern Medical Center / Chinese Academy of Medical Sciences / Chinese Academy of Sciences & Yunnan Province / DED / Cancer Institute / National Nature Science Foundation of China / Kunming Institute of Zoology / University of Texas / /

Person

Yang X. Interdimer / Chunghong Yan / Shi Y. Molecular / Dixit / V / Gang Liu / James Zhijian Chen / Guoning Liao / Gabriel NunĖœez / /

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Position

Boldin MP / standard WB / WB / Yunnan Province High-Profile Scientist / Hunter / Fisher / /

Product

cisplatin / sodium bicarbonate / Glustal W / TNT / S5B / /

ProvinceOrState

Texas / Wisconsin / Michigan / South Dakota / Manitoba / Yunnan Province / Yunnan / /

PublishedMedium

Cancer Research / /

Technology

siRNA / antibodies / Biotechnology / WB protocol / Cell Signaling / Apoptosis / gene expression / /

URL

www.nature.com/cddis / /

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