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ACE inhibitors / Carboxylic acids / Tetrazoles / Enantiopure drugs / Antihypertensive drug / Valsartan / Captopril / Management of heart failure / Renin-angiotensin system / Chemistry / Organic chemistry / Angiotensin II receptor antagonists


The past, present and future of renin–angiotensin aldosterone system inhibition
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Document Date: 2013-08-14 08:59:19

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City

Ann Arbor / Madrid / Losartan / Durham / Florence / New York / Nancy / Chicago / /

Company

Servier / Hunt SA / Novartis / Amgen / ACE / Forrest Laboratories / LVSD HF / I.L.P. / Williams B. Management / Severe HF / Academy Please / DebioPharm S.A. / GlaxoSmithKline / Merck / New York Heart Association HF / GE Healthcare / Astra / Takeda Pharmaceuticals / Chronic HF / Johnson & Johnson / Bayer / LG / Aventis / BP / Solvay / Elsevier Ireland Ltd. / Lilly / Symptomatic HF / McCormack T / Cytokinetics / Protein Design Laboratories / Medtronic / Collaborative Group / systolic HF / HP / AstraZeneca / /

Country

Switzerland / France / United Kingdom / Italy / Sweden / United States / Spain / /

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Event

FDA Phase / Funding / Reorganization / /

Facility

University of Glasgow / stable CAD / National Institute / American College of Cardiology Foundation/American Heart Association Task Force / Centre d'Investigations Cliniques / University of Michigan School / American College of Cardiology/American Heart Association Task Force / American College of Cardiology / University of Gothenburg / University Hospital / USA The University of Chicago Medicine / Weir MR / Montefiore-Einstein Medical Center / University of Lausanne / Duke University Medical Center / Associazione Nazionale Medici Cardioligi Ospedalieri Research Center / /

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IndustryTerm

treatment of acute and chronic heart failure / candesartan / prevention of cardiovascular disease / diuretic / treatment of preserved cardiac function heart failure / /

MedicalCondition

JE / primary hypertension / left ventricular dysfunction / cardiometabolic syndrome / artery disease / essential hypertension / unstable angina/non-ST-elevation myocardial infarction / renovascular hypertension / increased stroke / clinical disease / breast pain / albuminuria / acute and chronic heart failure / severe renal failure / ST-elevation myocardial infarction / fatal coronary heart disease / coronary heart disease / end-stage renal disease / renal dysfunction / severe heart failure / i.e. hyperkalemia / CV disease / preserved cardiac function heart failure / ventricular dysfunction / chronic heart failure / sudden cardiac death / atherogenesis / endothelial dysfunction / stroke / diastolic dysfunction / stable coronary artery disease / diabetes / Progressive renal dysfunction / diseases / Serious hyperkalemia / systolic heart failure / incident and resistant hypertension / renal failure / primary aldosteronism / Dry cough / e.g. gynecomastia / hospitalized angina / vascular disease / anterior myocardial infarction / symptomatic heart failure / transient ischemic attack / obesity / renal disease / key heart failure / non-insulin-dependent diabetes / hypertension study / Trial name Heart failure / gynecomastia / hypotension / acute myocardial infarction / proteinuria / hyperkalemia / congestive heart failure / non-fatal stroke / Diabetic nephropathy / chronic stimulation / i.e. hypertension / hypertension / disease / atherosclerosis / kidney disease / resistant hypertension / losartan hypertension / symptomatic hypotension / Arterial disease / chronic systolic HF / cardiovascular disease / myocardial infarction / suspected acute myocardial infarction / sleep apnea / heart failure / Angioedema / Severe congestive heart failure / thrombosis / myocardial ischemia / reduced stroke / /

MedicalTreatment

cardioversion / polypharmacy / alternative therapy / drug therapies / /

OperatingSystem

ISIS / /

Organization

University of Chicago Medicine / Chicago / Society for Cardiovascular Angiography and Interventions / Clinical Excellence / BHF Glasgow Cardiovascular Research Centre / Montefiore-Einstein Medical Center / Northwestern University Feinberg School of Medicine / Association of ACE2 / National Institute for Health and Clinical Excellence / New York Heart Association / Heart Failure Association / Task Force on the Management of ST-Segment Elevation Acute Myocardial Infarction / The American College / Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure / Society of Thoracic Surgeons / Centre d'Investigations Cliniques / American Heart Association Task Force on Practice Guidelines / University of Glasgow / Glasgow / Associazione Nazionale Medici Cardioligi Ospedalieri Research Center / Center for Cardiovascular Innovation / Food and Drug Administration / University Hospital / European Society of Cardiology / University of Michigan School of Medicine / National Institute for Health / University of Gothenburg / The University of Chicago / European Medicines Agency / American Heart Association / Japanese Society of Hypertension / International Society for Heart and Lung Transplantation / Duke University Medical Center / University of Lausanne / Lausanne / Data Monitoring Board / /

Person

John J.V. McMurray / Robert J. Mentz / Bernard Waeber / Van de Werf / Karl Swedberg / Ileana L. Piña / Mona Fiuzat / Luis M. Ruilope / Electrolyte Metab / Aldo P. Maggioni / Arch Intern / Christopher M. O'Connor / George L. Bakris / /

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Position

investigator / Miner / consultant / Corresponding author / Strawn WB / /

Product

losartan / Aldactone / Telmisartan / lisinopril / digoxin / EUROPA / captopril / Trandolapril / atenolol / Valsartan / irbesartan / Ramipril / Samsung S73 Digital Camera / Chlorthalidone / spironolactone / indapamide / hydrochlorothiazide / LCZ696 / HF / /

ProvinceOrState

New York / Michigan / North Carolina / /

PublishedMedium

the International Journal / /

Technology

apoptosis / CAD / Transplantation / pharmacokinetics / /

URL

http /

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