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Oncogenes / Proteins / Tumor suppressor genes / Wnt signaling pathway / Beta-catenin / Myc / Luciferase / NUMB / Colorectal cancer / Biology / Signal transduction / Genes


Shi et al. BMC Chemical Biology 2012, 12:4 http://www.biomedcentral.com[removed]
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San Francisco / Simon / Carlsbad / Hercules / Valencia / Billerica / Memphis / Cambridge / Indianapolis / Gibbstown / New Haven / Montgomery / St. Louis / /

Company

Boston Biochem Inc. / Millipore Corporation / EMD Chemicals Inc. / Roche Diagnostics / Sigma-Aldrich / Invitrogen Corporation / Proc Natl Acad Sci U S A / Qiagen / Bethyl Laboratories Inc. / BioMed Central Ltd. / Bio-Rad / Creative Commons / /

Country

United States / /

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Event

FDA Phase / /

Facility

Jude Children's Research Hospital / National Cancer Institute / Tcf complex / University of California / /

IndustryTerm

similar chemical structures / acidic side chain / free energy / htdrogen bonding energy / distal ubiquitin binding site / chemical compounds / surface energy / chemical library / torsional energy / chemical inhibitors / energy / similar chemical structure / electrostatic network / high binding free energy / catalytic site / cysteine catalytic site / electrostastic energy / modeled catalytic site / /

MarketIndex

Top 40 / /

MedicalCondition

adenomatous polyposis coli / Cutaneous cancer / colorectal cancer / colorectal tumor / familial adenomatous polyposis / inherited and sporadic colorectal cancer / adenocarcinoma / cancers / cancer metastasis / tumor / colon carcinoma / cancer / lung adenocarcinoma metastasis / limb deficiency / intestinal cancer / HCT116 colorectal cancer / ovarian tumor / malignant human squamous cell carcinomas / /

MedicalTreatment

chemotherapy / /

Organization

National Cancer Institute / National Institute of Health / Yale University School of Medicine / St. Jude Children's Research Hospital / Department of Pharmacology / Department of Structural Biology / University of California / San Francisco / /

Person

Luc Trbd / Yong Zhang / Xiaofeng Li / Hoanh Tran / /

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Position

high reporter / Walker / Wnt reporter / TOPFLASH reporter / author / Jacobson MP / representative / reporter / Repasky MP / /

Product

Glide / for / /

ProvinceOrState

Connecticut / Tennessee / California / New Hampshire / /

PublishedMedium

Journal of Medicinal Chemistry / /

Technology

Proteomics / molecular modeling / siRNA / stem cells / RNAi Codex algorithm / gene expression / DNA sequencing / chemotherapy / selected using the RNAi Codex algorithm / /

URL

http /

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