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Cell biology / Apoptosis / Programmed cell death / RNA / Cell division cycle 7-related protein kinase / P53 / A549 cell / MiR-138 / Small interfering RNA / Biology / Genetics / MicroRNA


MiR-630 inhibits proliferation by targeting CDC7 kinase, but maintains the apoptotic balance by targeting multiple modulators in human lung cancer A549 cells
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Document Date: 2014-09-25 08:35:50

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File Size: 2,31 MB

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City

Shanghai / Beijing / London / Santa Cruz / /

Company

Life Technologies / Amersham Biosciences / Macmillan Publishers Limited / /

Country

Taiwan / United States / United Kingdom / China / /

Currency

pence / /

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Event

FDA Phase / Product Issues / /

Facility

S-phase checkpoint / Capital Medical University / St Mary’s Campus / Peking University Health Science Center / University of Imperial College London / /

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IndustryTerm

cancer therapy / target site / miRNA processing / hybridized solution / /

MedicalCondition

human cancers / serum starvation / Human breast cancer MCF7 / several cancer / either tumor / tumor / cancer / Disease / human cancer / late apoptosis/necrosis / /

MedicalTreatment

cancer therapy / /

MusicGroup

PI / /

Organization

Capital Medical University / Peking University Health Science Center / Department of Biochemistry and Molecular Biology / University of Imperial College London / /

Person

Peter Cherepanov / Yong-Feng Shang / /

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Position

genotoxic stress J-X Cao / RT / operative / Luciferase reporter / Representative / specific RT / fragmentcontaining reporter / forward / reporter / Stem-loop RT / /

Product

cisplatin / penicillin / G1 / RevertAidTM First Strand / /

ProvinceOrState

South Dakota / /

PublishedMedium

Molecular Biology / /

Technology

siRNA / antibodies / hybridization / Biotechnology / ATM / Cell Signaling / apoptosis / DNA synthesis / gene expression / treating cancer / http / 3g / /

URL

www.pnas.org/cgi/content/short/1016574108 / http /

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