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City Fludarabine / Dallas / Cairo / / Company Ball / Singer / Wilson / Sun / / Country Belgium / United States / / Currency USD / / / Facility Blood Institute / Washington University / St Louis Children’s Hospital / / IndustryTerm magnetic resonance imaging / cord product / stem-cell products / healthcare / adequate sibling cord products / stem-cell product / cord products / imaging / transplant protocols / peripheral blood products / good quality cord product / pediatric age / banking / / MedicalCondition predetermined disease / malignant and nonmalignant disorders / strokes / ischemic strokes / Tricuspid regurgitation / Seizures / Flu / intracranial hemorrhage / sterility / acute chest syndrome / sickle cell anemia / endothelial injury / dysfunction / severe aplastic anemia / primarily acute chest syndrome / haploidentical donor Stroke Elevated TCD velocity Acute chest syndrome VOE Pulmonary / leukocytosis / Albuminuria / beta-thalassemia / malignant disorders / pulmonary / thalassemia major / Cerebrovascular accidents / Cerebral thrombosis / lowered seizure / mild disease / disorder / overt strokes / adequate chronic transfusion therapy Inability / thalassemia / aplastic anemia / severe disease / Osteonecrosis/AVN Red cell alloimmunization Silent stroke / overt stroke / graft versus host disease / second cancers / chronic blood transfusion therapy recipients / avascular necrosis / SS disease / hemoglobinopathies / infertility / sinusoidal obstruction syndrome / leukemia / cerebral disease / established organ dysfunction / priapism / chronic transfusion therapy / hypertension / disease / multifaceted injury / TBI / genetic disorder / host disease / stroke / cognitive impairment / onset cerebral infarction / pulmonary hypertension / nonmalignant disorders / sickle cell disease Introduction Sickle cell disease / initial stroke / myelodysplasia / pulmonary dysfunction / chronic transfusion setting / severe sickle cell disease / sickle cell disease / infection / inflammation / Thrombosis / avascular necrosis/osteonecrosis / syndrome / chronic transfusion therapy Pulmonary hypertension Recurrent stroke / disorders / Hb S-β thalassemia / / MedicalTreatment blood transfusion / Bone Marrow Transplant / radiation / gene therapy / total body irradiation / / Organization Center for International Blood / Division of Pediatric Hematology/Oncology / Center for International Blood and Marrow Transplant Research / Marrow Transplant Research / St Louis Children’s Hospital / Washington University / / Person Shalini Shenoy / Aquino / V / Stroke Elevated / Woo Ahn / Ann N Y Acad Sci / / Position Hb / Author / Major / / Product hydroxyurea / cyclophosphamide / thiotepa / / ProvinceOrState Kansas / / Technology radiation / polymerization / transplantation / Perl / stem cells / transplant protocols / ATG / MRI / gene therapy / magnetic resonance imaging / genotype / / URL http / SocialTag