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Metabolism / Fatty acids / Rare diseases / Coenzymes / Cellular respiration / Fatty-acid metabolism disorder / Carnitine / Fatty acid metabolism / Beta oxidation / Biology / Chemistry / Health


Treatment of cardiomyopathy and rhabdomyolysis in long-chain fat oxidation disorders using an anaplerotic odd-chain triglyceride Charles R. Roe,1 Lawrence Sweetman,1 Diane S. Roe,1 France David,2 and Henri Brunengraber2
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Document Date: 2012-05-31 13:41:17

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City

Carlsbad / Dallas / Beverly / Pointe Claire / Cleveland / Raleigh / New York / Evansville / /

Company

acyl-CoA / McGraw-Hill / SASOL GmbH / Invitrogen Corp. / /

Country

Canada / Germany / United States / /

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Event

Product Issues / Judicial Event / FDA Phase / /

Facility

Case Western Reserve University / Institute of Metabolic Disease / Baylor University Medical Center / /

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IndustryTerm

therapy for long-chain fat oxidation disorders / oddcarbon diet protocol / chemical improvement / energy / treatment for a number of disorders / energy source / treatment of long-chain fat oxidation disorders / gas chromatography / oil / energy production results / energy production / organ systems / investigative protocol / treatment of these disorders / chemical / energy deprivation / dietary treatment protocol / oil containing trioctanoin / /

MedicalCondition

hypertrophic cardiomyopathy / myopathy / hypoglycemic seizures / I glycogenosis / chronic elevation / persistent hypertrophic cardiomyopathy / chronic cardiomyopathy / injury / disorder / acute and chronic cardiomyopathy / tracheitis / illness / hypoglycemia / mitochondrial fat oxidation disorders / asthma / chronic medications / cardiomyopathy / respiratory failure / chronic / long-chain fat oxidation disorders / muscle pain / bilateral maxillary sinusitis / lethargy / vomiting / chronic disease / diseases / infection / hypotonia / deficiency / inherited metabolic disorder / disorders / cardiac and respiratory failure / otitis / acute cardiomyopathy / pericardial effusion / leg pain / muscle weakness / cardiomegaly / peripheral neuropathy / fatigue / intermittent rhabdomyolysis / profound hypoglycemia / myoglobinuria / infections / hypotonia / metabolic acidosis / VLCAD deficiency / congestive heart failure / disease / gastroenteritis / mild left ventricular hypertrophy / hypothermia / Mild concentric left ventricular hypertrophy / recurrent hypoglycemia / Diagnosis (age) Cardiomyopathy / rhabdomyolysis / pain / progressive peripheral neuropathy / Metabolic Disease / acute infection / syndrome / /

MedicalTreatment

physical therapy / low-fat diet / resuscitation / antibiotic therapy / fluid therapy / Atkins diet / fat-free diet / treatment protocol / /

Organization

Institute of Metabolic Disease / Baylor University Medical Center / US Federal Reserve / FDA / National Institute of Health / Case Western Reserve University / Cleveland / /

Person

Horst Schulz / Christine Vianey-Saban / Charles R. Roe / Robert A. Harris / Howard Sprecher / J.D. Cook / Jane Kao / Patrick Finnegan / /

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Position

Major / /

Product

C3 / digoxin / glycine / prednisone / fluticasone propionate / Flovent / C14 / VLCAD enzyme / cell lines / enzyme / /

ProvinceOrState

Ohio / Quebec / Indiana / New York / California / Texas / North Carolina / Massachusetts / /

PublishedMedium

The Journal of Clinical Investigation / /

Technology

dietary treatment protocol / gas chromatography / metabolite profiling / oddcarbon diet protocol / /

SocialTag