| Document Date: 2008-05-12 15:14:34
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City Rahway / New Haven / / Company Pfizer / Merck Research Laboratories / / Country Jordan / United States / / / Event Product Release / / Facility Sumneytown Pike / Yale University / / IndustryTerm informed chemical intervention / unmodified natural product / clearthe / pharmaceutical industry / large pharmaceutical / electrophilic metabolite chemical assay / vascular systems / chemical toxicology / pharmaceutical / faster synthetic technologies / chemical structure / computational tools / / MedicalCondition both acute and delayed-phase chemotherapy-induced nausea / vomiting / obesity / diseases / particular cancer / / MedicalTreatment chemotherapy / / Organization National Institute of Health / Yale University / Department of Chemistry / / Person M. Chen / R. M. Kohli / C. T. Walsh / Nat / H. Reichenbach / V / T. A. Keating / M. G. Thomas / / Position driver / synthetic chemist / already nal chemist / medicinal chemist / synthetic and medicinal chemist / chemist / D. J. / C. G. Marshall / / Product EMEND / Tao / taxol / / ProvinceOrState New Jersey / Pennsylvania / Connecticut / / Technology combinatorial chemistry / pharmacokinetics / drug metabolism / Drug Delivery / DRUG DISCOVERY / artificial intelligence / rational drug design / high-throughput screening / chemotherapy / computational chemistry / drug design / faster synthetic technologies / drug development / / URL www.sciencemag.org / /
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SPECIAL SECTION DRUG DISCOVERY References and Notes 1. D. E. Cane, C. T. Walsh, C. Khosla, Science 282, 63