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Alcohol abuse / Neurotransmitters / Stimulants / Substance dependence / Local anesthetics / Disulfiram / Cocaine / Cocaethylene / Alcoholism / Chemistry / Medicine / Organic chemistry


T he anti-alcoholism drug disulfiram (Antabuse), which is an inhibitor of aldehyde dehydrogenase, induces an aversive reaction to alcohol consumption and thereby helps patients reduce alcohol intake. Recent clinical tri
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City

Roset / Atlanta / Rounsaville / /

Company

A1 / Russell / Liles L.C. / Flynn D.D. / Wilson / Issue 4 179 Review / A2 / Ball S.A. / Human Laboratory / J. Pharm / /

Event

Product Recall / Product Issues / /

Facility

National Institutes of Health National Institute of Drug Abuse / National Institute of Drug Abuse / /

IndustryTerm

rubber factory / noradrenergic and dopaminergic systems / /

MedicalCondition

headaches / F. Pronounced paranoia / cocaine-induced paranoia / headache / alcohol abuse / cocaine abuse / facial flushing / nausea / cocaine users / P. Chronic / paradoxical hypersensitivity / chronic relapsing disorder / fatigue / behavioral hypersensitivity / acute and chronic disulfiram treatment / chronic norepinephrine deficiency / foot shock / hypersensitivity / paranoia / alcoholism / receptors Hypersensitivity / hypotension / insomnia / outpatient alcoholism / chronic inhibition / disease / flushing / maintenance employee alcoholism / vertigo / cocaine dependence / DBH Inhibition Chronic cocaine users / cocaine addiction / vomiting / drug abuse / cocaine-induced seizures / Reinstatement Drug addiction / /

MedicalTreatment

pharmacotherapies / behavioral therapy / psychotherapy / cognitive behavioral therapy / pharmacotherapy / /

MusicGroup

Yes / /

Organization

Meriem Gaval-Cruz and David Weinshenker Department of Human Genetics / Food and Drug Administration / National Institute of Drug Abuse / Disulfiram administration / Emory University School of Medicine / /

Person

Erwin / V / David Weinshenker / Robert Malison / A. Disulfiram / Hime / Monda / V / AL DH DBH / Cheryl Strauss / Arch Biochem / Schroeder / /

Position

mediator / General / Dean / Winger / /

Product

Antabuse / cocaine / disulfiram / animals / /

ProvinceOrState

P.N. / Georgia / /

RadioStation

CBT / /

Technology

CBT / pharmacokinetics / drug delivery / pharmacodynamics / genotype / /

SocialTag