Proc Natl Acad Sci U S A / Marsters SA / Ansell / Suzuki / /
Country
Germany / Ireland / / /
Event
Judicial Event / FDA Phase / /
Facility
University of Leipzig / Markus Rehm2 / 3 Abstract TRAIL / Boehm Institute of Pharmacology / TRAIL Combination Treatments Synergistic / TRAIL Endogenous TRAIL / Soluble TRAIL / Rehm TRAIL / Royal College of Surgeons / TRAIL Signaling / Jeremias I. TRAIL / Decoy Receptors TRAIL / / /
IndustryTerm
treatment of cancers / cancer therapy / cancer therapies / molecular machinery regulating apoptosis signal transduction / cell death machinery / Cancer Therapeutics / treatment of cancer / subsequent signaling network / zinc-binding site / /
MedicalCondition
JE / multiple myeloma / non small cell lung carcinoma / solid tumors CD20 / hematologic cancer / human tumor / refractory cancers / human acute leukemia / apoptosis-inducing cancer / thrombotic thrombocytopenic purpura / small cell lung cancer / melanoma / Apo-2L/tumor necrosis / non-small cell lung cancer / TRAIL-resistant hepatocellular carcinoma / Apo2L/tumor necrosis / human hepatoma cells / Apo2 ligand/tumor necrosis / leukemia / tumor / Cancer / advanced cancers / tumors / NSCLC / hepatocellular carcinoma / fulminant liver injury / advanced solid tumors / both solid and nonsolid malignant neoplasms / KRAS-mutant CRC Solid tumors / Mapatumumab Cytokines IFN-g Hepatocellular carcinoma / BMC Cancer / Non-Hodgkin lymphoma / infection / human hepatocellular carcinoma / isolated cancer / refractory colorectal cancer / DF / refractory non-Hodgkin lymphoma / lymphoma / et al. DR4-selective tumor necrosis / colorectal cancer / advanced non-squamous non-small-cell lung cancer / metastasis / attenuated disease / hepatitis C / J Cancer / EGFR-positive tumor / Combination Therapies Cancers / nonrafts mediate tumor necrosis / promyelocytic leukemia / MS / otherwise resistant cancers / liver steatosis / pancreatic cancer / cancers / non-Hodgkin's lymphoma / acute leukemia / mantle cell lymphoma subjects / tumour / advanced cancer / Designed tumor necrosis / human malignant neoplasms / certain cancers / tumor necrosis / tumor metastasis / Lexatumumab Hepatocellular carcinoma / Mol Cancer / acute myelogenous leukemia / spontaneous tumor / /
MedicalTreatment
radiation / cancer therapy / combination chemotherapies / cancer therapies / radiation therapy / /
Organization
Department of Physiology and Medical Physics / University of Leipzig / Leipzig / European Union / DED / American Association for Cancer Research / Health Research Board Ireland / Science Foundation Ireland / U.S. Food and Drug Administration / Royal College of Surgeons in Ireland / 1Rudolf Boehm Institute of Pharmacology and Toxicology / Irish Government / /
Person
Ib Ib / II II / Mol Med / Markus Rehm / Laurence J. Synergistic / Jong S. Playing / / /
Molecular Cancer Therapeutics Review