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City Buffalo / Neenah / Ruddle / Campbell / New York / Hsinchu / La Jolla / Billerica / Los Angeles / Cupertino / Tiwari-Woodruff / / Company Kimberly-Clark / Simonian N.A. / Perini / Bernstein / Andalman A.S. / Wilson / Bock N.A. / Leica Microsystems Inc. / Shriver L.P. / CelExplorer Labs / Jackson Laboratories / Shimizu / List Biological Laboratories / Elsevier Inc. / / Country Taiwan / United States / / / Facility Fort Wayne / Bar Harbor / Westwood Plaza / CNSI Advanced Light Microscopy/Spectroscopy Shared Resource Facility / University of California / / IndustryTerm optical clearing technology / intact biological systems / High-resolution imaging / intact imaging / chemical approach / magnetic resonance imaging / microscopic imaging / fresh clearing solution / water-based clearing solution / nitrogen gas / highresolution imaging / electrophoresis devices / pipeline processing environment / neuronal networks / imaging / uorescence imaging / food / micro-imaging gradient insert / in vivo imaging / in vivo magnetic resonance imaging / image processing / hydrophilic optical clearing solution / Quantitative magnetic resonance imaging / dedicated electrophoretic equipment / resolution using chemical cocktails / neuronal microtubule network / unobstructed brain imaging cocktails / nal clearing solution / / MedicalCondition Gray-matter injury / acute multiple sclerosis / typical clinical disease / Mean peak disease / Introduction Multiple sclerosis / experimental autoimmune encephalomyelitis / clinically early multiple sclerosis / clinical disease / axonal dysfunction / injury / mean clinical disease / multiple sclerosis / early reversible axonal dysfunction / demyelination / MS / acute experimental autoimmune encephalomyelitis / clinically early relapsing-remitting multiple sclerosis / disease / Pertussis / Mycobacterium tuberculosis / axonal injury / cortical multiple sclerosis / Huntington's disease / cognitive impairment / Alzheimer's disease / Intracortical multiple sclerosis / chronic demyelination / mild cognitive impairment / autoimmune disease / putative autoimmune demyelinating disease / neurodegenerative diseases / experimental allergic encephalomyelitis / both acute inflammatory demyelination / / MedicalTreatment Adoptive transfer / booster immunization / / Organization UCLA / University of California / Los Angeles / Los Angeles / Brain Mapping Center / Animal Research Committee / National Multiple Sclerosis Society / Department of Neurology / Conrad N. Hilton Foundation / David Geffen School of Medicine / / Person Rhonda Voskuhl / Matthew Schibler / Florian Kurth / Chandler R.L. Mongerson / Nat / Rory D. Spence / Stephen Sawiak / Perry / V / Shannon H. Wailes / Noriko Itoh / Mavis S. Peng / Ted Pella / Laurent Bentolila / / Position Archer / Chancellor / General / Brain Surface Extractor / Corresponding author / Bishop / Fisher / / Product benzyl benzoate / soma / Franklin / / ProvinceOrState S.K. / New York / Mississippi / California / New Hampshire / / Technology alpha / CLARITY protocol / electrophoresis / MPEG / polymerization / optical clearing technology / image processing / MRI / laser / magnetic resonance imaging / Spectroscopy / http / 3G / / URL http / SocialTag