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DNA replication / DNA repair / Chromosomes / Telomere / Telomerase / Homologous recombination / Non-homologous end joining / DNA / Dyskeratosis congenita / Biology / Genetics / Gerontology


Apollo Contributes to G Overhang Maintenance and Protects Leading-End Telomeres
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Document Date: 2014-05-05 14:05:23


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File Size: 1,79 MB

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City

New York / Phoenix / Santa Cruz / /

Company

Elsevier Inc. / QIAGEN / HA.11 Ab / Covance / Jackson Labs / /

Country

United States / /

Currency

pence / /

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Event

Product Issues / /

Facility

Memorial Sloan Kettering Cancer Center / The Rockefeller University / terminal FLAG / /

IndustryTerm

replication machinery / protein-docking site / loxP site / docking site / /

MedicalCondition

telomere dysfunction disease dyskeratosis congenita / additional telomere dysfunction / pWzl-Cre infection / bone marrow failure syndrome / hypersensitivity / infections / Cre infection / Hoyeraal-Hreidarsson syndrome / Apollo ORF / MEFs using two infections / disease / telomere dysfunction / infection / deficiency / HoyeraalHreidarsson syndrome / /

Organization

MRN DSB / SNM1 / Department of Molecular Biology / Memorial Sloan Kettering Cancer Center / Rockefeller University / /

Person

Apollo Gene Targeting / GACGATGCCA TACC TTGGCTC / CACGGTGGGTTTGT CTAGC / CTCC CATCA CTGCTTGCCTC / Apollo Mutants / Apollo Occurs / Apollo Contributes / Apollo Loss / Greg Hannon / /

Position

Representative telomeric overhang analysis / forward / /

Product

penicillin / protein / leading-end telomere fusions / cells / overhang maintenance / /

ProvinceOrState

New York / Chk2 / /

PublishedMedium

Molecular Biology / /

Technology

antibodies / hybridization / directed mutagenesis / ATM / cloning / Genotyping / stem cells / DNA synthesis / gene targeting / genotype / recombination / /

SocialTag