| Document Date: 2015-03-26 19:23:33
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Company Merck Sharp & Dohme Corp. / Merck & Co. Inc. / / Currency pence / / IndustryTerm Stroke Prevention / food / / MedicalCondition severe myopathy / chronic alcoholic liver disease / atherosclerotic vascular disease / primary hypercholesterolemia therapy / cholecystitis / CNS Toxicity Atorvastatin Brain hemorrhage / HIV / lymphatic system disorders / cholelithiasis / Hyperkalemia Infections / headache / myopathy / Skin disorders / mixed hyperlipidemia / urinary tract infection / subcutaneous tissue disorders / primary hypercholesterolemia / Nausea / Muscle spasms / anaphylaxis / muscle weakness / hepatitis C / toxic epidermal necrolysis / Stevens-Johnson syndrome / Homozygous Familial Hypercholesterolemia / spontaneous abortions / significant inflammation / Injury / single tonic convulsion / tendon rupture Immune system disorders / hemorrhagic stroke / erythema multiforme / poisoning / Myopathy/Rhabdomyolysis / Hypersensitivity / myoglobinuria / diarrhea / hepatitis / familial hypercholesterolemia / nonfatal hemorrhagic stroke / memory loss / serious liver injury / liver disease / hemorrhagic and lacunar stroke / Gastrointestinal disorders / proximal muscle weakness / CONTRAINDICATIONS Active liver disease / hypotension / Abdominal pain / Insomnia / fetal deaths / chronic process / CHD / Atherosclerosis / arthralgia / nasopharyngitis / hypothyroidism / Primary Hyperlipidemia / chronic treatment / amnesia / Carcinogenesis / uncontrolled seizures / electrolyte disorders / fatal and non-fatal hepatic failure / Brain hemorrhage / Primary Hyperlipidemia LIPTRUZET / stroke / cognitive impairment / Active liver disease / muscle pain / hyperlipidemia / fever / fatal hemorrhagic stroke / rhabdomyolysis / uncontrolled hypothyroidism / pain / Recent Stroke / angioedema / severe acute infection / muscle aches / autoimmune myopathy / increased ALT / connective tissue disorders / V dyslipidemias / renal failure / rash / immune-mediated necrotizing myopathy / paresthesia / cholestasis / acute renal failure / hypercholesterolemia / thrombocytopenia Nervous system disorders / / MedicalTreatment Oral contraceptives / apheresis / major surgery / Drug therapy / / Organization Concomitant administration / DOSAGE AND ADMINISTRATION / FDA / Cytochrome P450 3A4 Concomitant administration / / / Position General / / Product efavirenz / itraconazole / cyclosporine / niacin / gemfibrozil / Clarithromycin / erythromycin / cimetidine / Rifampin / LIPTRUZET tablets / Digoxin / ketoconazole / spironolactone / norethindrone and ethinyl estradiol / fenofibrate / LIPTRUZET capsule / Cholestyramine / / Technology Pharmacokinetics / Pharmacodynamics / / URL www.fda.gov/medwatch / /
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