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Apoptosis / Proteins / Peripheral membrane proteins / Immune system / Bcl-2 / Bcl-xL / BH3 interacting-domain death agonist / AKT / MCL1 / Biology / Cell biology / Programmed cell death


IP3R2 levels dictate the apoptotic sensitivity of diffuse large B-cell lymphoma cells to an IP3R-derived peptide targeting the BH4 domain of Bcl-2
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Document Date: 2014-07-18 10:44:40

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File Size: 3,05 MB

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City

PFEIFFER / SUDHL / Leuven / Wako / TOLEDO / Cleveland / Chieti / OCI / /

Company

IgG / IP3Rs / Macmillan Publishers Limited / /

Country

Italy / Belgium / France / United States / /

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Event

Product Issues / /

Facility

University of G. d’Annunzio / University Hospitals / Case Western Reserve University / Laboratory of Molecular / laboratory of Dr. A. Letai / RIKEN Brain Science Institute / /

IndustryTerm

Vehicle solution / /

MedicalCondition

IP3R2-expressing cancer / DL-BCL tumors / chronic lymphocytic leukemia / DL-BCL cancer / Some cancer / B-cell lymphomas / myeloid-cell leukemia / molecular mechanisms rendering cancer / IP3R3-expressing cancer / cancer / Disease / diffuse large B-cell lymphoma / diffuse large B-cell lymphoma cells / chronic activation / B-cell lymphoma malignant cells / B-cell lymphoma cells / B-cell lymphoma / B-cell cancer / /

MedicalTreatment

chemotherapy / /

Organization

Case Western Reserve University / RIKEN Brain Science Institute / Laboratory of Molecular and Cellular Signaling / University of G. d’Annunzio / Department of Cellular and Molecular Medicine / Institut Fe´de´ratif de Neurobiologie / Department of Neuroscience and Imaging / /

Person

Shi Targeting / Alfred Fessard / /

/

Position

*Corresponding author / executioner / Representative / /

Product

dimethyl sulfoxide / Ca2 / /

ProvinceOrState

Ohio / South Dakota / /

Technology

Neuroscience / antibodies / siRNA / apoptosis / Gif / gene expression / chemotherapy / /

URL

www.nature.com/cddis / /

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