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Focal adhesion / Integrin / Vinculin / Mechanotransduction / Cell adhesion / Talin protein / Stress fiber / Rho-associated protein kinase / Cytoskeleton / Biology / Cell biology / Cell signaling


Mechanosensation through integrins: Cells act locally but think globally Donald E. Ingber* Vascular Biology Program, Departments of Pathology and Surgery, Children’s Hospital and Harvard Medical School, Boston, MA 0211
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Document Date: 2012-09-28 18:11:19


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City

Schwarz / Akiyama / Boston / /

Company

Safran / Geisse N. A. / /

Country

United States / /

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Event

Movie Release / /

Facility

Children’s Hospital / square ECM / /

IndustryTerm

pharmaceutical applications / elegant new microarray-based mechanosensor technology / real-time analysis / signal transduction machinery / chemical signaling cascades / physical and chemical cues / silicon chip / therapies for hypertension / microfluidics systems / contractile machinery / microcontact printing technique / /

MedicalCondition

cancer metastasis / intestinal dysfunction / hypertension / disease / cardiac failure / pulmonary hypertension / diseases / asthma / /

Movie

A. D. / /

Organization

Harvard Medical School / Children’s Hospital / /

Person

Nat / Mooney / Donald E. Ingber / /

Position

D. J. / molecular cell biologist / Butler / engineer / /

ProvinceOrState

S. K. / Massachusetts / /

Technology

silicon chip / polymerization / biochips / lithography / microarray-based mechanosensor technology / microfluidics / photolithography / apoptosis / /

URL

www.pnas.org兾cgi兾doi兾10.1073兾pnas.0530201100 / /

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