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RNA interference / Organelles / Apoptosis / Programmed cell death / Myc / Mitochondrial disease / Mitochondrion / Human mitochondrial genetics / Mitochondrial DNA / Biology / Genetics / RNA


GLTSCR2/PICT1 links mitochondrial stress and Myc signaling John C. Yoona,b,c,1,2, Alvin J. Y. Linga,d,1, Meltem Isika,e, Dong-Young Donna Leea,b, Michael J. Steinbaugha,e, Laura M. Sacka,b, Abigail N. Boducha,b, T. Keith
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Document Date: 2014-11-05 15:20:43


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City

Boston / /

Company

TS CR 2 B co / IgG / Life Technologies / dPaul F. Glenn Laboratories / Myc shRNA1 2 3 Day co / Millipore / Takara / Agilent / GlaxoSmithKline / COX / Wiman KG / D.A.S. / /

Currency

pence / /

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Event

Product Issues / /

Facility

Massachusetts General Hospital / Howard Hughes Medical Institute / Ambion Silencer Select Human Genome siRNA Library / Harvard Medical School Institute / Institute of Chemistry / Women’s Hospital / ORFeome library / eJoslin Diabetes Center / bHoward Hughes Medical Institute / /

IndustryTerm

energy / mitochondrial import machinery / mitochondrial signaling networks / /

MedicalCondition

glioma tumor / different ORF / putative tumor / Mitochondrial disorders / ORF / human tumors / primary mitochondrial disorders / gliomas / median ORF / pooled ORF / human diseases / Mitochondrial diseases / age-related diseases / MS / colorectal and esophageal cancers / tumor / mitochondrial dysfunction / chemically induced skin cancers / cancer / disease / each ORF / glioblastoma cell lines / 19q-arm glioma tumor / individual ORF / metabolic syndrome / mitochondrial myopathy / infection / potential tumor / human disease / respiratory chain disorders / /

MedicalTreatment

radiation / /

NaturalFeature

MT DR / FITC channel / Ryan MT / MT DR FACS / /

Organization

Harvard Medical School / TS CR / United Mitochondrial Disease Foundation / DC CP / Women’s Hospital / Massachusetts General Hospital / Department of Genetics / bHoward Hughes Medical Institute / CR GP / Division of Genetics / Brigham and Women / Paul F. Glenn Foundation / US Federal Reserve / Institute of Chemistry and Cell Biology / eJoslin Diabetes Center / Howard Hughes Medical Institute / Juvenile Diabetes Foundation / Harvard Medical School Institute for Chemistry and Chemical Biology / /

Person

Stephen J. Elledgea / Stain / Abigail N. Boducha / Ai / David A. Sinclaira / Alvin J. Y. Linga / John C. Yoona / Stephen J. Elledge / Michael J. Steinbaugha / Laura M. Sacka / Dong-Young Donna Leea / Yoon et al. Myc / T. Keith Blackwella / /

Position

investigator / Author / downstream mediator / scientific consultant / reporter / key downstream mediator of GLTSCR2 signaling / /

Product

doxycycline / M-9 / cytochrome c-oxidase activity / /

ProvinceOrState

Massachusetts / /

PublishedMedium

PLoS ONE / /

RadioStation

Boisvert FM / /

Technology

Genomics / radiation / siRNA / Antibodies / Hybridization / high-throughput screening / cloning / Cell Signaling / Human Genome / apoptosis / artificial intelligence / DNA Chip / gene expression / cloning system / gene delivery / 3G / /

URL

www.pnas.org/lookup/suppl/doi / www.pnas.org/cgi/doi/10.1073/pnas.1400705111 / /

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