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(EGF−EGFR*)2−GAP + Grb2 −> (EGF−EGFR*)2−GAP−Grb2 (EGF−EGFR*)2−GAP + Shc −> (EGF−EGFR*)2−GAP−Shc (EGF−EGFR*)2−GAP−Shc + ATP −> (EGF−EGFR*)2−GAP−Shc* + ADP
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