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City PASMC / Geneva / Zurich / TNF / Interestingly / / Company MCI / Erwig LP / AMP / Mitsialis SA / Google / Honda / Comhair SA / COX / Price LC / Creative Commons / BioMed Central Ltd. / Waxman AB / Huber LC / / Country Switzerland / / / Facility University Hospital Zurich / / IndustryTerm e-publication / attractive tool / literature search / online submission / / MedicalCondition COPD-related pulmonary hypertension / pulmonary hypertension Alexandra Groth1 / cirrhosis waiting / inflammatory processes / endothelial injuries / macrophage-mediated inflammatory angiogenesis / pulmonary arterial hypertension / chronic renal failure / pulmonary endothelium / Connective tissue diseases / Systemic disorders / chronic thromboembolic pulmonary hypertension / cirrhosis / Schistosomiasis / lymphangioleiomyomatosis / vascular injury / perivascular fibrosis / pulmonary vasculature / microRNAs Introduction Pulmonary hypertension / pulmonary inflammation / liver cirrhosis / inflammatory injuries / pulmonary diseases / right ventricular hypertrophy / Metabolic disorders / mediastinitis / severe disease / inflammatory diseases / Recombinant tumor necrosis / systemic sclerosis / asthma / portopulmonary hypertension / pulmonary arteries / anti-TNF Therapy Against Congestive Heart Failure / Adult-Onset Still’s Disease / autoimmune disorders / pulmonary endothelial cells / human pulmonary artery smooth muscle cells / hypoxic pulmonary hypertension / Sleep-disordered breathing / lung inflammation / CCR7 deficiency / pulmonary hemodynamics / primary pulmonary hypertension / mean pulmonary arterial pressure / endotoxemicshock-induced pulmonary hypertension / important inflammatory cytokines / pulmonary vascular resistance / cultured human pulmonary artery smooth muscle cells / Gaucher disease / inflammatory component / pulmonary histiocytosis / Huber1* Abstract Pulmonary hypertension / bronchiolitis / Fibrotic disease / different inflammatory cells / monocrotaline-induced pulmonary hypertension / severe primary pulmonary hypertension / Portal hypertension / Valvular disease / Systemic inflammation / pulmonary arterial pressure / tumor necrosis factor-α / both pulmonary arterial pressure / moderate-to-severe heart failure / infection / deficiency / inflammatory effects / rat pulmonary artery smooth muscle cells / pulmonary hypertension show / Conclusions Inflammatory / Alveolar hypoventilation disorders / inflammatory systemic disease / Interstitial lung disease / hypoxia-induced pulmonary hypertension / chronic pulmonary inflammation / COPD / inflammatory process / perivascular inflammation / ventricular diastolic dysfunction / pulmonary pressures / Chronic exposure / scleroderma and human immunodeficiency virus infection / Hyperthyroidism / progressive right heart failure / experimental pulmonary hypertension / sarcoidosis / ventricular systolic dysfunction / REVIEW Open Access Inflammatory / fatigue / glycogen storage disease / Inflammatory cytokines / experimental asthma / pulmonary vessels / Clin Exp Allergy / Pulmonary veno-occlusive disease / inflammatory cells / Immune and inflammatory cell involvement / Pulmonary artery smooth muscle cells / MS / idiopathic and familial pulmonary arterial hypertension / high altitude pulmonary edema implicating / human pulmonary hypertension / idiopathic pulmonary arterial hypertension / Persistent pulmonary hypertension / severe pulmonary hypertension / congenital cardiomyopathies / HIV infection / hypertension / pulmonary arterial smooth muscle cells / pulmonary capillary hemangiomatosis / inflammatory cytokine TNFα / disease / atherosclerosis / high-altitude pulmonary edema / dyspnea / severe pulmonary arterial hypertension / Chronic obstructive pulmonary disease / myeloproliferative disorders / connective-tissue diseases / thyroiditis / pulmonary hypertension / pulmonary lesions / pulmonary disease / mild pulmonary hypertension / higher pulmonary pressure / Tumor necrosis / left heart disease / monocrotaline-induced pulmonary arterial hypertension / pulmonary arterial remodeling / tumor necrosis factor / thyroid disorders / pulmonary vascular reactivity / pulmonary circulation / pulmonary pressure / inflammation / thrombosis / connective tissue disease / chronic haemolytic anemia / human disease / / MedicalTreatment bypass / heart catheterization / / Organization World Health Organization / Division of Pulmonology / University Hospital Zurich / New York Heart Association / Swiss National Science Foundation / Zurich Lung Foundation / / Person Hecker / Cool C / Takahashi / Krishna Kumar / Mol Med / / Position second messenger / arrow head / Schermuly RT / author / King / experimental model / Hassoun PM / Walker / Messenger / important mediator / / Product BAL / IL-6 / DV / IL-1 / adenosine / / RadioStation Pellicelli AM / Wengner AM / Kouri FM / Holmes AM / Zeiher AM / / Technology apoptosis / DNA Chip / PDH / alpha / antibodies / transplantation / / URL http / SocialTag