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City Perm / Minneapolis / Uppsala / Blocking / Valencia / Raleigh / Austin / Palo Alto / Lutherville / Neurosciences / Wetzlar / Cambridge / FITC / Cleveland / Detroit / Foster City / Sustained / San Diego / Geel / St. Louis / / Company Stenberger Monoclonals Inc. / IgG / Leica Microsystems / Vector Laboratories / DNAX Corp / Millipore / Sigma-Aldrich / Qiagen / 14 BD Biosciences / Creative Commons / BD Biosciences / Pharmacia / Vector Labs / PerkinElmer / TreeStar Inc. / / Country Germany / Sweden / Belgium / United States / / / Event FDA Phase / / Facility Clinic Institutional Animal Care / Lerner Research Institute / National Cancer Institute / The Cleveland Clinic / / IndustryTerm software version / / MedicalCondition chronic progressive forms / CD45hi inflammatory cells / attenuated tumor necrosis factor / Progressive multiple sclerosis / partial hind limb paralysis / reduced CNS inflammation / human peripheral autoimmune diseases / strain / Background Multiple sclerosis / focal inflammation / Huntington’s diseases / experimental autoimmune encephalomyelitis / CNS inflammatory cells / rheumatoid arthritis / complete hind limb paralysis / chronic/progressive disease / clinical disease / colitis / decreased demyelination / CNS inflammation / mg/ml Mycobacterium tuberculosis / Decreased inflammation / extensive demyelination / Experimental autoimmune encephalomyelitis EAE / multiple sclerosis / chronic phase / overall inflammation / demyelination / inflammatory cells / MS / progressive EAE Demyelination / autoimmune inflammation / inflammatory diseases / chronic EAE / white matter demyelination / non-CNS autoimmune diseases / asthma / both pro-inflammatory injury / sustained demyelination / both acute and chronic CNS injury / cancer / disease / paralytic autoimmune disease / acute inflammation / sustained paralytic disease / progressive disease / pertussis toxin / CNS diseases / PFA / both clinical disease / autoimmune inflammatory response / progressive autoimmune encephalomyelitis Carine Savarin1 / autoimmune disease / exhibited improved clinical disease / chronic progressive MS / inflammation / chronic progressive phase / inflammatory cell proliferation / Inflammatory / increased demyelination / acute and chronic forms / / MedicalTreatment immunization / / Organization National Cancer Institute / Cleveland Clinic Institutional Animal Care and Use Committee / Lerner Research Institute / / Person Robert Coffman / Reverse Transcriptase (Invitrogen) / Frederick / / Position mediator / RT / author / representative / / Product Sigma / IL-6 / / ProvinceOrState Ohio / Mississippi / / Technology alpha / apoptosis / Gene expression / / URL http /
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Astrocyte response to IFN-γ limits IL-6-mediated microglia activation and progressive autoimmune encephalomyelitis