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Organic acids / Antioxidants / Coenzymes / Orthomolecular medicine / Vitamin C / Microdialysis / Glutathione / Extracellular fluid / Hydrogen peroxide / Chemistry / Biology / Cell biology


Ascorbate in pharmacologic concentrations selectively generates ascorbate radical and hydrogen peroxide in extracellular fluid in vivo Qi Chen, Michael Graham Espey, Andrew Y. Sun, Je-Hyuk Lee, Murali C. Krishna, Emily S
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Document Date: 2010-05-17 21:04:01


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City

Hyslop / Rockville / Uppsala / North Chelmsford / Iowa City / Shelton / Wilmington / San Jose / /

Company

Fleming / Walsh SA / Taconic Laboratories / E.S. P.L.C. K.L. / Pauling / Charles River Laboratories / Albers AE / M.C.K. P.L.C. C. / Ames / PerkinElmer / A.Y.S. P.L.C. C. / /

Country

Sweden / /

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Facility

University of Iowa / National Institute of Diabetes / National Cancer Institute / Laboratory of Bioorganic Chemistry / Mayo Clinic / Laboratory of Biochemistry / /

IndustryTerm

protein-centered metal / predicted reaction products / treatment of some cancers / reagents/analytic tools / cell culture media / cancer treatment / reaction products / metal-centered proteins / /

MedicalCondition

JE / hepatitis C / MS / infections / cancers / Tumor / cancer / glycolysis-dependent cancer / Kidney Diseases / selective cancer / /

MedicalTreatment

alternative medicine / Radiation / antibiotic therapy / /

MusicGroup

EPR / /

Organization

National Cancer Institute / Ascorbate Administration / Gavage administration / Food and Drug Administration / i.v. administration / National Academy of Sciences / Laboratory of Bioorganic Chemistry / Laboratory of Biochemistry / i.v. and i.p. administration / Parenteral Administration of Ascorbate / Parenteral administration / National Institute of Diabetes and Digestive / i.p. administration / Intravenous administration / Animal Care and Use Committee / Center for Drug Evaluation and Research / University of Iowa / /

Person

Emily Shacter / Kenneth L. Kirk / Andrew Y. Sun / Michael Graham Espey / Peter L. Choyke / Chaya Pooput / Mark Levine / Garry R. Buettner / Murali C. Krishna / Hyuk Lee / /

Position

advocate enhanced basic and clinical research / King / Governor / Hunter / /

Product

Intraperitoneal injection / isoflurane / /

ProvinceOrState

Q.C. / Maryland / Iowa / /

RadioStation

Ferraris AM / /

Technology

Radiation / microwave / pharmacokinetics / /

URL

www.pnas.org兾cgi兾doi兾10.1073兾pnas.0702854104 / www.pnas.org/misc/reprints.shtml / www.pnas.org/misc/rightperm.shtml / www.pnas.org#otherarticles / /

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