Fatty acid synthase

Results: 13



#Item
1

A First-In-Human Study of the First-In-Class Fatty Acid Synthase (FASN) Inhibitor TVB-2640 Results of Dose Escalation in Mono and Combination and Evidence of Preliminary Activity A.  Brenner1, J. Infante2, M. Patel3, H

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Source URL: www.3vbio.com

- Date: 2015-11-06 13:32:52
    2Clinical medicine / Medicine / Lung cancer / Biology / KRAS / Non-small-cell lung carcinoma / Biomarker / Ras subfamily / FASN / Fatty acid synthase

    FASN inhibitor TVB-2640 shows pharmacodynamic effect and evidence of clinical activity in KRAS mutant NSCLC patients in a Phase 1 study Marie O’Farrell, Tim Heuer, Katharine Grimmer, Richard Crowley, Joanna Waszczuk, M

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    Source URL: www.3vbio.com

    Language: English - Date: 2016-04-19 06:39:33
    3Medicine / Combination therapy / Medical terminology / Pharmacology

    Preliminary Activity in the First in Human Study of the First-InClass Fatty Acid Synthase (FASN) Inhibitor, TVB-2640 M. Patel1, A. Brenner2, J. Infante3, HT. Arkenau4, E. Borazanci5, G. Falchook6, J. Lopez7, S. Pant8, E.

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    Source URL: www.3vbio.com

    Language: English - Date: 2016-03-24 18:34:04
    4Lipids / Stereochemistry / Carboxylic acids / Polyunsaturated fatty acid / Oxylipin / Linoleate diol synthase / Chirality / 9Z / Lipoxygenase / Chemistry / Fatty acids / Nutrition

    http://www.diva-portal.org Postprint This is the accepted version of a paper published in Methods in Molecular Biology. This paper has been peer-reviewed but does not include the final publisher proof-corrections or jou

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    Source URL: uu.diva-portal.org

    Language: English - Date: 2015-02-11 07:28:27
    5Cell biology / Intracellular receptors / Fibrates / Organochlorides / Peroxisome proliferator-activated receptor / Sterol regulatory element-binding protein / Gene expression / Bezafibrate / Fatty acid synthase / Biology / Transcription factors / Chemistry

    Proline- and acidic amino acid-rich basic leucine zipper proteins modulate peroxisome proliferatoractivated receptor α (PPARα) activity Frédéric Gachona,b,1, Nicolas Leuenbergerc,2, Thierry Claudeld, Pascal Gosa, Cé

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    Source URL: www.molbio.unige.ch

    Language: English - Date: 2011-06-10 04:05:34
    6Biochemistry / Fatty acids / Coenzymes / Thioesters / Biosynthesis / Fatty acid synthesis / Malonyl-CoA / Fatty acid synthase / Lipid / Metabolism / Chemistry / Biology

    Leading Edge Previews The Long and Short of Fatty Acid Synthesis Howard Riezman1,*

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    Source URL: cms.unige.ch

    Language: English - Date: 2011-11-29 05:56:16
    7Metabolism / Biology / Urea cycle disorder / Argininosuccinic aciduria / Argininosuccinate synthase / Newborn screening / Argininosuccinate lyase / Fatty-acid metabolism disorder / Carbamoyl phosphate synthetase I deficiency / Health / Urea cycle / Rare diseases

    Microsoft Word - ASAL 2013.doc

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    Source URL: www.newbornscreening.info

    Language: English - Date: 2014-05-21 21:47:42
    8Lipid / O-methyltransferase / Allelopathy / Fatty acid / Transferases / Biology / Polyketide synthase

    Microsoft Word - S-008.doc

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    Source URL: seas.iung.pulawy.pl

    Language: English - Date: 2004-07-05 04:52:43
    9Genetics / Essential amino acids / Proteinogenic amino acids / Gene expression / RNA / RNA interference / Acetolactate synthase / Disease resistance in fruit and vegetables / Herbicide / Biology / Chemistry / Branched-chain amino acids

    Fatty acid profiles and their distribution patterns in microalgae: a comprehensive analysis of more than 2000 strains from the SAG culture collection

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    Source URL: www.ncbi.nlm.nih.gov

    Language: English
    10Pathology / Prostate cancer / Urology / Prostate biopsy / Fatty acid synthase / Gleason Grading System / Prostate / Cancer / Medicine / Histopathology / Biopsy

    Hamada et al. BMC Clinical Pathology 2014, 14:3 http://www.biomedcentral.com[removed]RESEARCH ARTICLE Open Access

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    Source URL: www.ncbi.nlm.nih.gov

    Language: English
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